Rhopressa (Netarsudil)

Also Known as Rhokiinsa

Prescription medicineOnly Available By Prescription

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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

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Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Rhopressa (Netarsudil) is used to treat open-angle glaucoma or ocular hypertension. It does so by helping aqueous humor (fluid in the eye) drain better, resulting in reduced eye pressure. Despite the medication’s effectiveness, it’s unknown how exactly it works.

Fact Table

Formula

C28H27N3O5

License

US FDA

Bioavailability

Low (topical ophthalmic; minimal systemic absorption)

Legal status

Prescription only (Rx)

Chemical Name

Netarsudil

Elimination half-life

~16–20 hours (systemic)

Dosage (Strength)

0.02% ophthalmic solution (0.2 mg/mL), once daily in the evening

Pregnancy

Limited data; use only if potential benefit justifies risk

Brands

Rhopressa

Protein binding

~64%

PubChem CID

86287129

MedlinePlus

Not available

ChEBI

Not available

ATC code

S01EX06

DrugBank

DB11850

KEGG

Not available

Routes of administration

Ophthalmic (eye drops)

Directions

Want to buy Rhopressa eye drops (ophthalmic solution) at a low price? Consider buying here at Canada Drugs Direct, where additional Rhopressa discounts may apply to you. This medication is available as an ophthalmic solution in 0.02% strength.

One drop should be applied once daily directly into the affected eye, typically in the evening or as prescribed by your doctor. Do not exceed this daily dose, even if you miss one. In this case, simply continue with your next scheduled dose. Rhopressa eye drops are typically used long-term. Patients taking medications with similar effects must allow at least 5 minutes between doses of both medications.

Ingredients

The active ingredient in Rhopressa is netarsudil (0.02% strength).

Cautions

There are some cautions you should consider before taking Rhopressa eye drops. If you see signs of any of the following, notify your healthcare provider.

  • Eye pain or worsening vision can be a sign of eye surface swelling (Epithelial Corneal Edema). This is especially common in people with prior corneal issues or after undergoing certain eye surgeries.
  • Using Rhopressa might heighten your risk for eye infections (bacterial keratitis) if the dropper tip touches the eye, fingers, or other surfaces. This particularly applies to patients with corneal disease or eye surface injury. Keep the bottle tip clean, and avoid touching the eye while using this medication.
  • Remove contact lenses before using Rhopressa and wait for 15 minutes after application to place them back.
  • You may experience general eye irritation when using Rhopressa, including ongoing redness, discomfort or vision changes.
  • Do not use this medication in children as it hasn't been approved in this age group.

Contraindications

According to the FDA, there are no known contraindications of Rhopressa. Precautions still apply.

Side Effects

Some common side effects of Rhopressa are the following:

  • Eye redness
  • Swirl-shaped markings on the cornea (corneal verticillata)
  • Stinging or pain during use
  • Small blood spots on the white of the eye
  • Redness at the application site
  • Mild eye irritation of the eye surface or eyelids
  • Staining of the eye surface or eyelids
  • Watery eyes

More serious side effects include the following:

  • Corneal swelling
  • Eye irritation
  • Worsened vision
  • Severe pain

This is not a complete list of side effects. Any persistent or concerning side effects of Rhopressa should be reported to your doctor.

Looking to buy Rhopressa from Canada Drugs Direct? A valid prescription from your eye doctor is all that is required.

Learn about the Rhopressa eye drop price and available discounts today!

Frequently Asked Questions about Rhopressa (Netarsudil)


What is Rhopressa (Netarsudil) used for?

Rhopressa is a prescription eye drop used to lower elevated intraocular pressure in people with open-angle glaucoma or ocular hypertension. Reducing eye pressure helps protect the optic nerve and may slow vision loss associated with these conditions.


How does Rhopressa work?

Rhopressa works by increasing fluid drainage from the eye through the trabecular meshwork and by reducing fluid production and episcleral venous pressure. This combined action helps lower pressure inside the eye more effectively.


How is Rhopressa typically used?

Rhopressa is usually applied as one drop in the affected eye once daily in the evening. Using it more often than prescribed does not improve effectiveness and may increase side effects.


What are the most common side effects of Rhopressa?

The most common side effects include eye redness, mild eye discomfort, stinging or burning after application, and small blood spots on the white of the eye. These effects are usually mild to moderate and often lessen with continued use.


Can Rhopressa affect vision?

Rhopressa may cause temporary blurred vision immediately after application. This usually clears within a short time, but caution is advised when performing activities that require clear vision right after use.


Is Rhopressa safe to use with other glaucoma eye drops?

Rhopressa is often used alone or in combination with other glaucoma medications. When multiple eye drops are used, they are typically spaced several minutes apart to allow proper absorption.


Who should not use Rhopressa?

Rhopressa may not be appropriate for individuals with known hypersensitivity to netarsudil or any component of the formulation. A healthcare provider should evaluate suitability based on eye health and medical history.


Can Rhopressa be used during pregnancy or breastfeeding?

There is limited information on the use of Rhopressa during pregnancy or breastfeeding. A healthcare professional should assess potential risks and benefits before use in these situations.


What should be done if a dose of Rhopressa is missed?

If a dose is missed, it is generally applied the next evening as scheduled. Extra doses are not typically used to make up for a missed application.


How should Rhopressa be stored?

Rhopressa should be stored at room temperature and protected from light. The bottle should be kept tightly closed when not in use, and care should be taken to avoid contaminating the dropper tip.

IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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