Top brand choice
| Strength | Pack Size | Qty | |
|---|---|---|---|
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Strength
200mg
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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Rezurock (belumosudil) is a prescription medication used to treat chronic graft-versus-host disease (cGVHD) in adults and children 12 years and older. It belongs to a class of drugs called ROCK2 inhibitors, which block certain pathways in the body that drive inflammation. Rezurock is prescribed for patients whose cGVHD has not improved after at least two previous treatments, making it another option to help manage this condition.
Fact Table | |
Formula | C26H24N6O2 |
License | US FDA |
Bioavailability | 64% |
Legal status | Rx-only |
Chemical Name | 2-[3-[4-(1H-indazol-5-ylamino)quinazolin-2-yl]phenoxy]-N-propan-2-ylacetamide |
Elimination half-life | 19 hours |
Dosage (Strength) | 200mg tablet; 200mg orally once daily with food |
Pregnancy | May cause fetal harm; avoid pregnancy |
Brands | Rezurock |
Protein binding | 99.9% to human serum albumin; 98.6% to alpha-1 acid glycoprotein |
PubChem CID | 11950170 |
MedlinePlus | a621043 |
ChEBI | N/A |
ATC code | L04AA48 |
DrugBank | DB16703 |
KEGG | D11815; D11816 |
Routes of administration | Oral |
Take Rezurock once daily by mouth with or without food. The standard dosage is 200 mg taken at the same time each day. A doctor or healthcare provider may need to adjust the dose based on how well the medication is tolerated or if certain side effects develop. Swallow the tablets whole and don't crush, break, or chew them. Store the medication at room temperature away from moisture and heat.
Belumosudil is the active ingredient in this drug.
Before taking this medication, you may want to consult a healthcare provider about the following:
Rezurock may cause harm to an unborn baby. It should not be used during pregnancy, as studies in animals showed risks like miscarriage and birth defects.
Women who can become pregnant and men with partners who could become pregnant should use effective birth control while taking Rezurock. Contraception should also continue for at least one week after stopping treatment.
If you are pregnant, planning to become pregnant, or think you may be pregnant, talk to your doctor right away before starting or continuing Rezurock.
Avoid taking this medication if there’s a known hypersensitivity or allergy to any ingredients.
The most common side effects of Rezurock seen in studies include infections, tiredness or weakness, nausea, diarrhea, cough, shortness of breath, swelling, and muscle or joint pain. Some people also reported headache, stomach pain, rash, itching, or changes in blood pressure. Blood tests sometimes showed low phosphate, fewer lymphocytes, or higher liver enzyme levels.
More serious side effects may also happen and can lead to stopping or changing treatment. These include severe infections, heavy bleeding, trouble breathing, and problems with liver or kidney function. In rare cases, severe stomach or intestinal symptoms and multi-organ failure have been reported. Consult a healthcare provider if serious reactions develop.