Reyataz (Atazanavir)

Prescription medicineOnly Available By Prescription
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200mg
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150mg
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Reyataz (atazanavir) is a medication administered with other antiretroviral medications to treat HIV-1 infection in adults and pediatrics who are 3 months old or older and weigh a minimum of 5 kg.


Fact Table

Formula

C38H52N6O7

License

EU EMA, US DailyMed

Bioavailability

60-68%

Legal status

Rx-Only

Chemical Name

Atazanavir

Elimination half-life

6.5 hours

Dosage (Strength)

150mg, 200mg, 300mg

Pregnancy

Consult doctor

Brands

Reyataz

Protein binding

86%

PubChem CID

148192

MedlinePlus

a603019

ChEBI

37924

ATC code

J05AE08

DrugBank

DB01072

KEGG

D01276

Routes of administration

By mouth

Directions

Reyataz comes in 150 mg, 200 mg, and 300 mg oral capsules and a 50 mg oral powder packet.

The instructions that are on your prescription's label and in the package insert should be followed. Talk to your doctor or pharmacist if you have any questions or concerns.

Recommended Dosing

Treatment-naive adults:

  • Take Reyataz 300 mg by mouth with ritonavir 100 mg by mouth once daily with food. 
  • For patients who are unable to tolerate ritonavir, it is recommended to take Reyataz 400 mg by mouth once daily with food. 
  • Take Reyataz 400 mg by mouth with ritonavir 100 mg by mouth once daily if taking efavirenz.

Treatment-experienced adults:

  • Take Reyataz 300 mg by mouth with ritonavir 100 mg by mouth once daily with food. 
  • Take Reyataz 400 mg by mouth with ritonavir 100 mg by mouth once daily if taking with H2RA and tenofovir DF.

Pediatric patients: 

  • Body weight determines dosing with the Reyataz oral capsules. The dose should not be greater than the adult dose. Do not take on an empty stomach. 

Reyataz oral powder:

  • Take it with ritonavir; do not take on an empty stomach. Do not use it in pediatric patients who do not weigh at least 5 kg.

Pregnancy:

  • Take Reyataz 300 mg by mouth with ritonavir 100 mg by mouth once daily with food. 

Dose adjustments:

  • The dose of Reyataz may require adjustment based on other medications, kidney function, and liver function.

Ingredients

The active ingredient in Reyataz capsules and oral powder is Atazanavir sulfate, an HIV-1 protease inhibitor. 

Crospovidone, lactose monohydrate, and magnesium stearate are the inactive ingredients contained in Reyataz capsules. Gelatin, FD&C Blue No. 2, titanium dioxide, black iron oxide, red iron oxide, and yellow iron oxide are the inactive ingredients that make up the shells of the capsules. The ink that is printed on the capsules contain shellac, titanium dioxide, FD&C Blue No. 2, isopropyl alcohol, ammonium hydroxide, propylene glycol, n-butyl alcohol, simethicone, and dehydrated alcohol.

Aspartame, sucrose, and orange-vanilla flavor are the inactive ingredients included in Reyataz oral powder.

Contraindications

Avoid taking Reyataz if you have an allergy to atazanavir or any of the other ingredients contained in Reyataz.

You should not take Reyataz with alfuzosin, amiodarone (if Reyataz is given with ritonavir), triazolam, oral midazolam, ergo derivatives, rifampin, irinotecan, lurasidone (if Reyataz is given with ritonavir), lovastatin, simvastatin, lomitapide, indinavir, cisapride, pimozide, St. John's wort, nevirapine, elbasvir/grazoprevir, glecaprevir/pibrentasvir, and sildenafil (when dosed as Revatio). Ask your doctor if you have any questions about whether or not you take these medications.

Cautions

  • Before beginning use of Reyataz, be sure to talk to your doctor about:
    • Any allergies you may have
    • Any medical problems or conditions you may have
    • Medications you take
    • If you are pregnant or breastfeeding
  • Reyataz can induce problems with cardiac conduction and prolong the PR interval. Discuss your risks with your doctor.
  • Reyataz can induce serious skin reactions. Immediately let your doctor know if you develop a rash or other skin reactions or conditions.
  • Elevations in indirect bilirubin levels can be caused by Reyataz. 
  • Patients who have phenylketonuria can be harmed by the phenylalanine that is found in Reyataz oral powder. 
  • Liver injury or damage can be caused by Reyataz. If you have hepatitis B or C, you may be at risk. 
  • Kidney problems can be caused by Reyataz.
  • Kidney stones and gallstones can be caused by Reyataz.
  • Diabetes mellitus and high blood sugar levels, immune reconstitution syndrome, and body fat redistribution or accumulation can be caused or worsened by Reyataz.
  • Bleeding in patients who have hemophilia type A and B can be caused by the use of Reyataz.

Side Effects

Side effects of Reyataz include nausea, yellowing of the skin and eyes, rash, headache, stomach pain, vomiting, trouble sleeping, peripheral neurological problems, dizziness, muscle pain, diarrhea, depression, and fever. These are not all of the possible side effects that can occur with Reyataz. Immediately inform your doctor if you have troublesome or continuous side effects. 

Reference:

Reyataz (atazanavir). Princeton NJ: Bristol-Myers Squibb Company; 2020.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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