Canada Drugs Direct

Visiting from Canada?

Want to save up to 80% on your medications? Signup below to be notified if we open a Canadian Online Pharmacy.

I agree to receive email updates from Canada Drugs Direct

Looking for Call us toll free 1-800-500-2897

Wait! Don't leave yet... $20 Off Your first order

Use Coupon Code: OZPOPUP20

* Please remember this coupon code above and enter it during checkout

Rexulti (Brexpiprazole)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
Pack Size
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Rexulti (brexpiprazole) is an atypical antipsychotic used with antidepressants for the treatment of major depressive disorder (MDD) in adults and for the treatment of schizophrenia in adults and pediatric patients who are at least 13 years old.

Rexulti tablets are available in 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, and 4 mg strengths.


Rexulti is taken once daily by mouth. It can be taken with or without food.

MDD in adults

Starting dose: 0.5 mg/day or 1 mg/day

Recommended dose: 2 mg/day

Max dose: 3 mg/day

Schizophrenia in adults

Starting dose: 1 mg/day

Recommended dose: 2 to 4 mg/day

Max dose: 4 mg/day

Schizophrenia in pediatric patients (13-17 years old)

Starting dose: 0.5 mg/day

Recommended dose: 2 to 4 mg/day

Max dose: 4 mg/day


Brexpiprazole is the active ingredient in Rexulti.


You should not take Rexulti if you are allergic to brexpiprazole or any of the other ingredients in Rexulti. Talk to your doctor about your allergies.



See full prescribing information for complete boxed warning.

  • Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at increased risk of death. REXULTI is not approved for the treatment of patients with dementia-related psychosis.
  • Antidepressants increased the risk of suicidal thoughts and behaviors in patients aged 24 years and younger. Monitor for clinical worsening and emergence of suicidal thoughts and behaviors. Safety and effectiveness of REXULTI have not been established in pediatric patients with MDD.

Rexulti can cause neuroleptic malignant syndrome. Neuroleptic malignant syndrome is a serious condition and can lead to death. Seek medical attention immediately if you develop a high fever, problems breathing, changes in blood pressure, changes in heart rate, muscle stiffness, confusion, or sweating.

Rexulti can cause involuntary movements of your face, tongue, or other parts of the body, even after you stop taking it.

Let your doctor know if you have diabetes. Rexulti can cause your blood sugar levels to increase. Tell your doctor if you develop excessive thirst or hunger, feel sick to your stomach, need to urinate more frequently, feel weak or tired, feel confused, or your breath smells fruity.

Rexulti can cause increased cholesterol and triglycerides.

Rexulti can cause weight gain. Monitor your weight while taking Rexulti.

Rexulti can cause compulsive urges. Talk to your doctor if you experience unusual, compulsive urges.

Rexulti can cause low white blood cell counts.

Let your doctor know if you have blood pressure problems. Rexulti can cause your blood pressure to drop upon standing.

Rexulti can cause sleepiness or dizziness which can cause you to fall, increasing your risk for fractures or other injuries. 

Let your doctor know if you have seizures. Rexulti can increase your risk for seizures.

Tell your doctor about any medications you take, including prescription and over-the-counter medications, vitamins, and supplements.

Side Effects

Rexulti can cause side effects, including:

  • Restless
  • Weight gain

Rexulti may cause other side effects. Contact your doctor right away if you experience bothersome side effects or side effects that will not go away.

With a valid prescription, you can purchase Rexulti online at a competitive price at Canada Drugs Direct.


  1. Rexulti. Rockville, MD: Otsuka America Pharmaceutical, Inc.; 2021.
  2. Rexulti. Accessed January 4, 2022.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

product-reviews Product Reviews