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AirDuo (Fluticasone propionate and Salmeterol)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
55/14mcg (60doses/inhaler)
Pack Size
232/14mcg (60doses/inhaler)
Pack Size

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


AirDuo RespiClick contains a corticosteroid, fluticasone propionate, and a long-acting beta2-adrenergic agonist (LABA), salmeterol, for the treatment of asthma in people 12 years of age and older.

AirDuo RespiClick should not be used for the relief of sudden breathing problems. AirDuo RespiClick is not a rescue inhaler and should not be used in replacement of one.

Fact Table






Negligible oral

Legal status


Chemical Name


Elimination half-life

9–11 hours

Dosage (Strength)

55/14mcg, 232/14mcg (inhaler)


Consult Doctor



Protein binding

96% - 99%

PubChem CID






ATC code






Routes of administration



AirDuo RespiClick is for oral inhalation. Follow the instructions that are given with your prescription. 

The inhalation powder is available in strengths of 55 mcg/14 mcg, 113 mcg/14 mcg, or 232 mcg/14 mcg of fluticasone propionate/salmeterol in each actuation.

Your starting dose will be based on the severity of your symptoms and previous treatment. 

The typical dose is to inhale one puff by mouth twice daily. Do not use a spacer or volume holder chamber with AirDuo RespiClick.


Fluticasone propionate and salmeterol xinafoate are the active ingredients in AirDuo RespiClick.


Do not use AirDuo RespiClick for the primary treatment of status asthmaticus or acute episodes of asthma requiring intensive therapy.

Talk to your doctor about your allergies. AirDuo RespiClick should not be used if you are severely allergic to milk proteins, fluticasone propionate, salmeterol, or any of the other ingredients in AirDuo RespiClick.


  • Tell your doctor about all the medications you take, including all prescription and over-the-counter medications, vitamins, and supplements.
  • The risk of asthma-related death is increased when a LABA is used alone for asthma treatment. The risk of asthma-related hospitalization in pediatrics is also increased when a LABA is used alone for asthma treatment.
  • Do not use AirDuo RespiClick during disease deterioration or life-threatening asthmatic episodes. Do not use AirDuo RespiClick as a rescue inhaler.
  • Do not use AirDuo RespiClick with other LABAs due to the risk of overdose that can lead to severe cardiovascular effects or death.
  • A fungal infection of the mouth and pharynx can develop with the use of AirDuo RespiClick. Be sure to rinse your mouth with water after using AirDuo RespiClick.
  • Tell your doctor if you have immune system problems or an existing infection. Worsening of tuberculosis and other infections can occur with the use of AirDuo RespiClick. 
  • Use caution and slowly taper if you are being switched from a systemic corticosteroid to AirDuo RespiClick.
  • Hypercorticism and adrenal suppression can occur with the use of AirDuo RespiClick. 
  • Discontinue AirDuo RespiClick right away and seek alternative treatment if you experience trouble breathing after using AirDuo RespiClick.
  • Let your doctor know about any heart problems or central nervous system disorders you have. 
  • Decreases in bone mineral density can occur with AirDuo RespiClick. Tell your doctor if you have a family history or if you have weak bones. Tell your doctor if you do not get a lot of exercise.
  • Growth of pediatric patients should be monitored during treatment with AirDuo RespiClick. 
  • Tell your doctor if you have cataracts or glaucoma. Regular eye exams are recommended during treatment with AirDuo RespiClick.
  • Eosinophilic conditions like Churg-Strauss Syndrome may develop with the use of AirDuo RespiClick. 
  • Tell your doctor if you have convulsive disorders, thyroid problems, diabetes mellitus, or ketoacidosis.
  • Contact your doctor right away if you develop the following:
    • Symptoms of hypokalemia (low potassium levels in the blood): irregular heart rhythms, muscle cramps, muscle twitches
    • High blood sugar levels
  • Let your doctor know if you are pregnant or plan to become pregnant.
  • Let your doctor know if you are breastfeeding or plan to breastfeed.

Side Effects

AirDuo RespiClick can cause side effects. The most common include common cold, fungal infection of the mouth, back pain, cough, and headache.


  1. AirDuo RespiClick Prescribing Information. Parsippany, NJ: Teva Pharmaceuticals USA, Inc.; 2021.
  2. AirDuo RespiClick (fluticasone propionate 113 mcg and salmeterol 14 mcg). Accessed January 25, 2022. 
  3. Low Potassium Levels in Your Blood (Hypokalemia). Cleveland Clinic. Last reviewed March 12, 2018. Accessed January 31, 2022.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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