Rectiv Ointment (Glyceryl Trinitrate)

Prescription medicineOnly Available By Prescription

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Strength Pack Size Qty
0.4% 30 grams
Pack Size

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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Rectiv ointment is a prescription medication used to treat chronic anal fissures.

It contains the active ingredient glyceryl trinitrate, which works by relaxing the smooth muscles of the anus and promoting blood flow to the area, which can help to heal the fissure.

Fact Table






Less than 1%

Legal status


Chemical Name

Glyceryl trinitrate

Elimination half-life

3 minutes

Dosage (Strength)

0.4% 30 grams


Consult Doctor



Protein binding


PubChem CID






ATC code






Routes of administration



Before using Rectiv ointment, wash the affected area with mild soap and water, and then gently pat dry.

Apply a small amount of the medication to the area around the anus, usually twice daily, in the morning and at bedtime.


The active ingredient in Rectiv ointment is glyceryl trinitrate.


Rectiv may have drug-drug interactions with:

  • Alcohol
  • Alfuzosin
  • Alteplase
  • Amifostine
  • Amisulpride
  • Anticholinergic Agents
  • Antipsychotic Agents
  • Apomorphine
  • Barbiturates
  • Benperidol
  • Blood Pressure Lowering Agents
  • Brimonidine
  • Bromperidol
  • Dapoxetine
  • Dapsone
  • Diazoxide
  • DULoxetine
  • Ergot Derivatives
  • Heparin
  • Herbal Products with Blood Pressure Lowering Effects
  • Hypotension-Associated Agents
  • Levodopa-Containing Products
  • Local Anesthetics
  • Lormetazepam
  • Molsidomine
  • Naftopidil
  • Nicergoline
  • Nicorandil
  • Nitric Oxide
  • Nitroprusside
  • Obinutuzumab
  • Pentoxifylline
  • Pholcodine
  • Phosphodiesterase 5 Inhibitors
  • Prilocaine
  • Prostacyclin Analogues
  • Quinagolide
  • Rilmenidine
  • Riociguat
  • Rosiglitazone
  • Sodium Nitrite


Rectiv ointment should not be used if you are allergic to glyceryl trinitrate or any other ingredient in the medication.

It is important to avoid getting the medication in your eyes, as it can cause irritation and redness. Wash your hands after application.

Do not use Rectiv ointment if you are pregnant or planning to become pregnant, as it may harm the developing fetus.

Side Effects

Tell your doctor if you experience any of these side effects:

  • Abdominal pain
  • Application site irritation
  • Asthenia
  • Contact dermatitis
  • Diaphoresis
  • Dizziness
  • Drowsiness
  • Dyspnea
  • Exfoliative dermatitis
  • Fixed drug eruption
  • Flushing
  • Headache
  • Hypersensitivity reaction
  • Hypotension
  • Hypoxemia
  • Lactic acidosis
  • Methemoglobinemia
  • Nausea
  • Nonimmune anaphylaxis
  • Orthostatic hypotension
  • Pallor
  • Palpitation
  • Paresthesia
  • Peripheral edema
  • Pharyngitis
  • Rebound hypertension
  • Restlessness
  • Rhinitis
  • Shock
  • Skin rash
  • Syncope
  • Tachycardia
  • Vertigo
  • Vomiting


Rectiv Ointment [package insert]. Bedminster, NJ: ProStrakan, Inc; 2011.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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