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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Ravicti (glycerol phenylbutyrate) is a nitrogen-binding agent indicated for the chronic management of urea cycle disorders (UCDs) in patients who cannot be managed by dietary protein restriction and/or amino acid supplementation alone. It works by providing an alternative pathway for nitrogen excretion through the formation of phenylacetylglutamine, which is excreted via the urine. Ravicti is not indicated for the treatment of acute hyperammonemia and is suitable for use in both pediatric patients (aged 2 months and older) and adults. The oral liquid formulation is nearly tasteless and odorless, enhancing adherence in long-term treatment.
| Fact Table | |
| Formula | C21H37NO5 |
| License | US FDA (2013) |
| Bioavailability | Converted to phenylbutyrate; effective absorption >90% |
| Legal status | Prescription only |
| Chemical Name | Glycerol phenylbutyrate |
| Elimination half-life | ~2 hours (phenylacetic acid, active metabolite) |
| Dosage (Strength) | 1.1 g/mL oral liquid |
| Pregnancy | Category C – Risk cannot be ruled out |
| Brands | Ravicti |
| Protein binding | Phenylacetic acid: ~80% |
| PubChem CID | 16069903 |
| MedlinePlus | a613030 |
| ChEBI | 141487 |
| ATC code | A16AX11 |
| DrugBank | DB08909 |
| KEGG | D10352 |
| Routes of administration | Oral (liquid) |
Ravicti should be administered orally, typically three times daily with meals or feedings. The dosage is individualized based on the patient's body surface area and estimated nitrogen waste output. It is essential to monitor plasma ammonia levels regularly to adjust dosing. Ravicti must be prescribed and used under the supervision of a healthcare professional experienced in managing urea cycle disorders. It should be used in conjunction with dietary protein restriction and, if needed, amino acid supplementation.
The active ingredient in Ravicti is glycerol phenylbutyrate. Inactive ingredients: None. Ravicti is composed solely of the active pharmaceutical ingredient in a liquid formulation without added excipients.
Ravicti is contraindicated in patients with known hypersensitivity to glycerol phenylbutyrate or any of its metabolites. It should not be used in patients with short-chain or medium-chain fatty acid oxidation disorders due to the risk of serious adverse metabolic events.
Use Ravicti with caution in patients with hepatic impairment, as metabolism may be altered. Regular monitoring of ammonia levels, plasma glutamine, and nutritional status is necessary to ensure therapeutic efficacy and prevent toxicity. In pediatric patients under two months of age, safety and effectiveness have not been established. Ravicti contains a triglyceride backbone, and care should be taken in patients with disorders involving fat metabolism.
Common side effects may include:
Serious adverse effects may include neurotoxicity due to elevated plasma levels of phenylacetate or phenylacetylglutamine. Monitoring is essential to mitigate this risk.
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If you have any questions at all, or would like to place an order, you are encouraged to contact us by toll-free
phone 1-888-904-8467 or email info@canadadrugsdirect.com.
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Canada Drugs Direct employs dedicated, professional licensed pharmacists to ensure that each and every order is reviewed before it is dispensed for the safety and health of our customers. At CanadaDrugsDirect.com, your health is our top priority.
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