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Rapamune (Sirolimus)

Prescription medicineOnly Available By Prescription
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1mg
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Rapamune is an immunosuppressant medication prescribed to prevent organ rejection in patients who have received a kidney transplant. 

Directions

Take Rapamune exactly as prescribed by your doctor. Never change the formulation you are using without talking to them first, or you may be at risk of transplant rejection.

Ingredients

Rapamune and Rapamune generic contain the active ingredient sirolimus.

Interactions

Drug-drug interactions increase the risk of transplant rejection. Never start a new medication before discussing it with your healthcare providers and transplant team.

Some of the common drug-drug interactions with Rapamune include:

  • Amiodarone
  • Apalutamide
  • Aprepitant
  • Atazanavir
  • Berotralstat
  • Bexarotene
  • Bosentan
  • Carbamazepine
  • Cenobamate
  • Ceritinib
  • Cimetidine
  • Clarithromycin
  • Cobicistat and cobicistat-containing coformulations
  • Conivaptan
  • Crizotinib
  • Cyclosporine
  • Dabrafenib
  • Darunavir
  • Dexamethasone
  • Diltiazem
  • Dronedarone
  • Duvelisib
  • Efavirenz
  • Enzalutamide
  • Erythromycin
  • Eslicarbazepine
  • Etravirine
  • Fedratinib
  • Fluconazole
  • Fosamprenavir
  • Fosaprepitant
  • Fosphenytoin
  • Grapefruit juice
  • Idelalisib
  • Imatinib
  • Indinavir
  • Isavuconazole (isavuconazonium sulfate)
  • Itraconazole
  • Ketoconazole
  • Lefamulin
  • Letermovir
  • Lonafarnib
  • Lopinavir
  • Lorlatinib
  • Lumacaftor
  • Mifepristone
  • Mitotane
  • Modafinil
  • Nafcillin
  • Nefazodone
  • Nelfinavir
  • Netupitant
  • Nilotinib
  • Ombitasvir-paritaprevir-ritonavir
  • Pexidartinib
  • Phenobarbital
  • Phenytoin
  • Posaconazole
  • Primidone
  • Ribociclib
  • Rifabutin
  • Rifampin (rifampicin)
  • Rifapentine
  • Ritonavir and ritonavir-containing coformulations
  • Saquinavir
  • Schisandra
  • St. John's wort
  • Telithromycin
  • Tucatinib
  • Verapamil
  • Voriconazole

Cautions

Your transplant team will perform therapeutic drug level monitoring while taking Rapamune and will regularly adjust your dose to make sure it’s therapeutic.

People taking Rapamune are at an increased risk of infection and an increased risk of certain types of cancers, including lymphoma.

Side Effects

Common adverse reactions with Rapamune can include:

  • Abdominal pain
  • Acne
  • Anemia
  • Arthralgia
  • Chest pain
  • Creatinine increase
  • Diarrhea
  • Dizziness
  • Fever
  • Headache
  • Hypercholesterolemia
  • Hypertension
  • Hypertriglyceridemia
  • Myalgia
  • Nasopharyngitis
  • Nausea
  • Pain
  • Peripheral edema
  • Stomatitis
  • Thrombocytopenia
  • Upper respiratory tract infection
  • Urinary tract infection

Visit Canada Drugs Direct to buy Rapamune and find a low Rapamune cost.

References

Rapamune [package insert]. Philadelphia, PA: Pfizer; 2017.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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