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Ragwitek (ragweed pollen allergen extract)

Prescription medicineOnly Available By Prescription

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Ragwitek is a prescription medicine used for sublingual (under the tongue) immunotherapy to treat short ragweed pollen allergies. As an allergen extract made from short ragweed pollen (Ambrosia artemisiifolia), Ragwitek targets the root cause of allergy symptoms related to ragweed, such as runny nose and itchy eyes, whether or not eye inflammation is present. It works by gradually increasing the body's tolerance to the allergen, helping to reduce the severity of symptoms caused by short ragweed pollen.


The standard dosage of Ragwitek is one tablet taken once daily. The tablet is placed under the tongue and allowed to dissolve in the mouth. Do not swallow for at least 1 minute to let the tablet dissolve completely.

Begin taking Ragwitek at least 12 weeks before the expected onset of the ragweed pollen season, and continue daily throughout the pollen season. Take the first dose in a clinic or hospital setting to monitor for any signs or symptoms of a severe allergic reaction for at least 30 minutes. Follow the prescribed dosing schedule and consult with a healthcare professional if any concerns or questions arise while undergoing treatment. Ragwitek is not intended to provide immediate relief from allergy symptoms, but rather helps your body develop immunity over time.


Ragwitek is a prescription medication that contains the active ingredient short ragweed pollen allergen extract derived from the Ambrosia artemisiifolia plant.


Avoid taking or using Ragwitek if any of the following apply:

  • A history of severe allergic reactions like anaphylaxis related to allergen immunotherapy
  • Existing severe or poorly managed asthma
  • Prior episodes of eosinophilic esophagitis
  • Known allergies to any ingredients present in the drug


  • Before you start taking Ragwitek (ragweed pollen allergen extract), consult a healthcare provider about the following:
    • Your existing medical conditions
    • Medications you're currently on
    • Whether you're pregnant or nursing
  • Be vigilant for severe, potentially fatal, allergic reactions while on this treatment. Look out for symptoms like skin hives, itching, difficulty breathing, or facial and throat swelling.
  • Should you experience any oral wounds or inflammation, it's recommended to temporarily stop the use of Ragwitek until your condition improves.
  • Ragwitek is intended for use in adults up to age 65. The medication will not provide immediate relief from allergy symptoms, so it's vital to continue with other allergy treatments while undergoing Ragwitek immunotherapy.
  • Ragwitek treatment should be carried out under the supervision of a healthcare professional familiar with potential side effects related to allergen immunotherapy.

Side Effects

Ragwitek may cause side effects in some individuals. Common side effects may include throat irritation, a prickling sensation in the mouth, and itching of the ears, mouth, and tongue,. These side effects are generally mild and may not require medical intervention.

Ragwitek may also cause more serious side effects that require immediate medical attention, such as severe dizziness, fast heart rate, cough, chest tightness, wheezing, trouble breathing, and swelling of the face, lips, tongue, or throat. If you take Ragwitek and experience any of these serious side effects, seek medical attention immediately.


Ragwitek Prescribing Information. Wiltshire, UK: ALK-Abelló A/S; 2022.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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