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Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

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  • We will only match the current advertised price.
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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Plenvu (polyethylene glycol 3350, sodium ascorbate, sodium sulfate, ascorbic acid, sodium chloride, and potassium chloride) is a prescription medication used for bowel cleansing before colonoscopy in adults. It's a low-volume bowel prep that is administered orally.

Fact Table


Variable composition mixture


FDA approved


N/A (not systemically absorbed)

Legal status


Chemical Name

Polyethylene glycol 3350, sodium ascorbate, sodium sulfate, ascorbic acid, sodium chloride, potassium chloride

Elimination half-life


Dosage (Strength)

Each pouch contains 100 g polyethylene glycol (PEG) 3350, NF; 9 g sodium sulfate, NF; 2 g sodium chloride, USP/NF; 1 g potassium chloride, USP/NF


Consult Doctor



Protein binding

Minimal/none expected

PubChem CID

Not applicable (mixture)


Not applicable (mixture)


Not applicable (mixture)

ATC code





No KEGG ID, chemical mixture

Routes of administration



Plenvu is available as a powder to be mixed with water and consumed as a solution. The box contains two pouches, Pouch A and Pouch B. The first dose (Pouch A) is typically taken in the evening before your colonoscopy followed by the second dose (Pouch B) the next morning. Mix each pouch with water to make a 500 ml solution and consume over 30 minutes, followed by at least 500 ml of clear liquids. Follow your healthcare provider's instructions on diet and fluid intake before your procedure.


The active ingredients in Plenvu solution are polyethylene glycol 3350, sodium ascorbate, sodium sulfate, ascorbic acid, sodium chloride, and potassium chloride.


Tell your healthcare provider about all the medications you're currently taking and about your medical history. Do not take Plenvu if you have a gastrointestinal obstruction, gastric retention, bowel perforation, toxic colitis or megacolon, or if you are allergic to any of the ingredients in Plenvu.


  • Before you start taking Plenvu, please tell your healthcare provider:
    • About all the medications you're currently taking, including over-the-counter drugs, prescription medications, and dietary supplements.
    • If you have a history of kidney problems, heart problems, seizures, or if you have trouble swallowing.
    • If you have phenylketonuria (PKU) as Plenvu contains aspartame.
    • If you have Glucose-6-phosphate dehydrogenase deficiency (G6PD). If you do, apply caution when using Plenvu.
    • If you are pregnant, planning to become pregnant, or are breastfeeding. The effects of Plenvu on unborn babies and breastfed children are unknown.
  • Plenvu can cause serious side effects, including serious loss of body fluid (dehydration) and changes in blood salts (electrolytes) in your blood. This could lead to abnormal heart rhythms, seizures, kidney problems, or death. If you have persistent vomiting or signs of dehydration such as dizziness, light-headedness, or urinating less than usual, stop taking Plenvu and contact your healthcare provider immediately.
  • For patients with a history of cardiac arrhythmias, it is recommended to have ECGs before and after the colonoscopy. 
  • Plenvu may cause mucosal ulcerations in patients with diagnosed or suspected inflammatory bowel disease. 
  • Patients at risk of aspiration should take Plenvu under medical supervision.
  • Plenvu may also cause allergic reactions. Seek medical attention immediately if you experience difficulty breathing, hives, swelling of your face, lips, tongue, or throat.
  • Be aware that Plenvu can potentially interfere with the absorption of other drugs, including oral contraceptives, which may lead to a decrease in their efficacy.

Side Effects

The most common side effects of Plenvu include nausea, vomiting, dehydration, and abdominal pain. If you experience any serious or persistent side effects, contact your healthcare provider.

The Plenvu cost may vary depending on your pharmacy and insurance coverage. With a valid prescription, you can also buy Plenvu online here!


  1. Plenvu Prescribing Information. Bridgewater, NJ: Salix Pharmaceuticals; 2021. 
  2. Plenvu (polyethylene glycol 3350, sodium ascorbate, sodium sulfate, ascorbic acid, sodium chloride, and potassium chloride) Solution. Important Safety Information. Accessed July 22, 2023.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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