Piqray (Alpelisib)

Prescription medicineOnly Available By Prescription

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Strength Pack Size Qty
50mg & 200mg
Pack Size
Pack Size
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Piqray (alpelisib) is a prescription medication for treating adults who have:

  • hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, advanced or metastatic breast cancer with PIK3CA-mutated gene that has progressed on or after endocrine-based treatment

Piqray comes in 50 mg, 150 mg, and 200 mg tablets for oral administration.


Piqray should be taken as your healthcare provider has directed. Read the medication guide thoroughly that accompanies your prescription.

Piqray dosing:

Your healthcare provider will determine an appropriate dose for you. The recommended dose is 300 mg by mouth once daily. Take with food.

Store Piqray tablets at room temperature between 68°F and 77°F (20°C and 25°C) and away from children.

Any questions or concerns may be referred to your healthcare provider or pharmacist.


Alpelisib is the active ingredient in Piqray.

Hypromellose, magnesium stearate, mannitol, microcrystalline cellulose, sodium starch glycolate, iron oxide black, iron oxide red, macrogol/polyethylene glycol (PEG) 4000, talc, and titanium dioxide are the inactive ingredients.


Piqray should not be given to patients who are allergic to any of its ingredients.


  • Before you start treatment with Piqray, inform your healthcare provider:
    • Of all the medications you take, including prescription and nonprescription medications, vitamins, herbals, and supplements
    • Of your allergies
    • Of your current health problems
    • Of your past medical history
    • If you are pregnant or breastfeeding
  • The following can occur during treatment with Piqray:
    • Hypersensitivity that may be severe
    • Cutaneous adverse reactions that may be severe
    • High blood sugar levels
    • Pneumonitis and interstitial lung disease
    • Diarrhea or colitis
    • Harm to a fetus. Females of childbearing potential and males with female partners who are of childbearing potential should be advised to use effective contraceptive methods during treatment with Piqray and for one week after receiving the final dose.
  • Breastfeeding is not advised.

Side Effects

Piqray side effects include but are not limited to high blood sugar levels; elevated creatinine; diarrhea; rash; decreased blood sugar levels, lymphocytes, and hemoglobin; increased gamma-glutamyl transferase (GGT), liver enzymes, and lipase; nausea; fatigue; decreased appetite; swelling/sores of the mouth; vomiting; weight loss; decreased calcium levels; hair loss; and prolonged blood clotting time. Contact your healthcare provider right away if you have bothersome or persistent side effects.

Here, you can buy Piqray!


Piqray. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2024.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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