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Paxlovid (Nirmatrelvir/Ritonavir)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Paxlovid is a combination antiviral therapy that targets the SARS-CoV-2 virus, which causes COVID-19. It consists of two medications, nirmatrelvir and ritonavir, working together to stop the virus's ability to multiply within the body. It is typically prescribed to treat non-hospitalized adults who have mild to moderate COVID-19 and are at an increased risk of developing severe symptoms, which may lead to hospitalization or worse.

Directions

Paxlovid should be taken orally with or without food as soon as possible after a diagnosis of COVID-19 and within five days of symptom onset. The standard regimen consists of two nirmatrelvir tablets and one ritonavir tablet, taken together twice daily for five days. Patients should complete the full course of therapy, even if they start to feel better before the period is up. Follow the instructions provided by a healthcare provider and on what's included in the box for proper administration.

Ingredients

Paxlovid consists of two active components, nirmatrelvir and ritonavir. In addition, Paxlovid contains several inactive ingredients to promote the stability and usability of the medication. These inactive ingredients improve the delivery and absorption of the active drugs and include:

  • Colloidal silicon dioxide
  • Polyethylene glycol
  • Microcrystalline cellulose
  • Sodium stearyl fumarate

Contraindications

Avoid taking this medication if any of the following apply:

  • Known allergies to nirmatrelvir, ritonavir, or any ingredients of the Paxlovid formulation.
  • Concurrent use of certain other medications that can cause serious or life-threatening reactions if used with Paxlovid, such as strong CYP3A4 inducers, which can greatly decrease Paxlovid's effectiveness, and drugs processed by the CYP3A enzymes.

Cautions

  • Before initiating Paxlovid therapy, have a detailed conversation with your healthcare provider about:
    • Any current medications you are taking
    • Existing health conditions, particularly liver or kidney issues
    • The potential risks to an unborn child or a nursing baby, as the effects of Paxlovid in these situations are not entirely understood
  • Paxlovid may affect the way your body processes other drugs. This interaction could occasionally lead to serious or even life-threatening consequences.
  • Regularly consult with your healthcare provider or pharmacist about possible drug interactions both when you start taking Paxlovid and throughout your course of treatment.
  • Should you experience symptoms of a severe allergic reaction, like difficulty in breathing, facial or throat swelling, or an intense skin rash, discontinue Paxlovid immediately and seek medical attention.
  • Some patients have reported liver-related issues, such as elevated liver enzymes, hepatitis, or jaundice, while on Paxlovid. Notify your healthcare provider if you experience signs of liver trouble, including skin or eye yellowing, dark-colored urine, or stomach pain.
  • For individuals with uncontrolled or undiagnosed HIV-1 infection, using Paxlovid might increase the risk of developing resistance to certain HIV treatments.

Side Effects

Paxlovid may cause a range of side effects, with some people experiencing mild reactions, while others may face more severe problems. Common Paxlovid side effects can include stomach pain, nausea, vomiting, high blood pressure, and headaches. Serious side effects, although rare, may require immediate medical attention.

Watch for signs or symptoms of an allergic reaction, such as hives, itching, swelling of the face or throat, or trouble breathing. Dark urine and clay-colored stools may indicate potential liver issues, which require an immediate consultation with a healthcare professional.

References:

  1. Paxlovid (Nirmatrelvir/Ritonavir) Product Monograph. New York, NY: Pfizer Laboratories; 2023.
  2. Paxlovid (Nirmatrelvir/Ritonavir) Drug Label Information. New York, NY: Pfizer Laboratories; 2023.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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