Paxil CR (Paroxetine)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
Strength
12.5mg
Pack Size
Qty
Strength
25mg
Pack Size
Qty
Strength
37.5mg
Pack Size
Qty

Top Generic choice

Strength Pack Size Qty
Strength
12.5mg
Pack Size
Qty
Strength
25mg
Pack Size
Qty
Strength
37.5mg
Pack Size
Qty
What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Paxil CR (Paroxetine) is a selective serotonin reuptake inhibitor (SSRI) used to treat depression, anxiety disorders, and premenstrual dysphoric disorder (PMDD). It works by increasing the levels of serotonin, a chemical in the brain that helps control mood. Paxil CR comes in a controlled-release form, which means the medicine is released into your body slowly throughout the day. This slow release can help reduce side effects and lets you take the medication just once a day.

Directions

Paxil CR should be taken as a single daily dose in the morning, with or without food. It’s important to swallow the tablet whole, without chewing or crushing it, to maintain its controlled-release properties. For adults, the typical starting dosage is 12.5 mg to 25 mg daily. For older adults, the initial dose is often 12.5 mg daily. Dosages may vary based on individual needs and should be managed by a healthcare provider.

Ingredients

The active ingredient in Paxil CR is Paroxetine.

Contraindications

Avoid taking or using this medication if any of the following apply:

Known hypersensitivity to Paroxetine

Concurrent use of monoamine oxidase inhibitors (MAOIs)

Recent discontinuation of an MAOI within 14 days

Use of Thioridazine or Pimozide

Cautions

Before taking Paroxetine, you may want to consult a healthcare provider about the following:

Any existing health conditions

Any allergies

A list of all medications you are currently taking

Whether you are pregnant or breastfeeding

Paroxetine may increase the risk of suicidal thoughts or behavior in people under 25, especially in the first few months of treatment or when the dose changes. This risk is highest for those with depression.

Taking Paroxetine with other medications that affect serotonin—like migraine drugs, some painkillers, antidepressants, or herbal supplements like St. John’s Wort—can lead to a rare but serious condition called serotonin syndrome. This can cause symptoms like agitation, fever, muscle stiffness, confusion, or seizures.

Paroxetine should not be taken with certain medications like Thioridazine or Pimozide, as doing so can affect heart rhythm and lead to serious heart problems.

Paroxetine may slightly increase the risk of birth defects, especially heart problems, if taken during the first trimester. Talk to your doctor if you’re pregnant or planning to become pregnant.

Paroxetine may increase the risk of bleeding, especially if taken with blood thinners. Watch for unusual bruising, bleeding, or nosebleeds and report them to your doctor.

In people with bipolar disorder, Paroxetine may trigger manic or mixed episodes. Before starting, your doctor may ask about any personal or family history of mood disorders.

Do not stop Paroxetine suddenly. Doing so may lead to nausea, dizziness, trouble sleeping, or mood changes. Your doctor will guide you on how to safely stop the medication.

Side Effects

Common side effects of Paxil CR include nausea, sleepiness, dry mouth, constipation, dizziness, and sexual problems in both men and women. Some people may also experience sweating, tremors, blurred vision, or trouble sleeping. These symptoms are usually mild and may improve as your body adjusts to the medication. However, if they persist or become bothersome, talk to your healthcare provider.

Paroxetine may also cause more serious side effects, including serotonin syndrome, low sodium levels, and seizures. It can increase the risk of abnormal bleeding, eye problems, or manic episodes in some individuals. Stopping this medication suddenly can lead to withdrawal symptoms such as irritability, mood changes, or electric shock sensations. Let your doctor know if you experience any serious reactions or need help managing side effects.

References

Paxil CR (Paroxetine) Product Monograph. Weston, FL: Apotex Inc.; 2024.

Paxil CR (Paroxetine) Drug Label Information. Weston, FL: Apotex Inc.; 2024.



IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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