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Parnate (Tranylcypromine)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Parnate is a prescription antidepressant medication that is usually prescribed for patients seen to have moderate to severe depression by their doctor. The active ingredient - tranylcypromine - inhibits the function of monoamine oxidase so that brain neurotransmitters are balanced more evenly. Parnate must be taken as regularly as indicated for the patients to see improvements and that may take up to 3 weeks from when they begin taking this antidepressant medication.

You can buy Parnate with a prescription, and your best price on it will be when you order medication online from Canada Drugs Direct.


Once you are prescribed and buy Parnate, then the standard starting dose for Tranylcypromine is 10mg 2x daily, once in the morning and once in the afternoon.

Doctor may increase dosage to 20 or 30mg depending on patients' response, as well as lower dosage over time if patient sees significant improvement with depression

Do not take a double dose if you forget to take your antidepressant one day. Failure to take medication for multiple days may reduce the effectiveness of treatment


The active ingredient in Parnate is Tranylcypromine.


Tell your doctor if you have any history of high blood pressure, heart disease, stroke, chronic headaches, adrenal gland problems, liver or blood disorders, or blood flow problems before starting on Parnate.

Tell your doctor if you have been taking any other antidepressant medications to date.

Store medication at room temperature and out of direct light.


There is the possibility of negative drug interactions between Parnate and other Rx medications, including buspirone / dextromethorphan / dibenzazepine derivatives like amitriptyline, nortriptyline, carbamazepine and cyclobenzaprine / levodopa / methyldopa / MAO inhibitors like phenelzine / selective serotonin reuptake inhibitors (SSRIs) other than fluoxetine / serotonin and norepinephrine reuptake inhibitors (SNRIs) like venlafaxine / triptan migraine medications like sumatriptan and rizatriptan.

Tell your doctor of all medications you are currently taking before getting a prescription and proceeding to buy Parnate online.

Side Effects

Parnate side effects are uncommon, but some users may experience constipation, decreased appetite, diarrhea, dizziness, drowsiness, dry mouth, nausea, trouble sleeping, or weakness. If side effects are seen, then you may want to discontinue use and speak to your doctor again regarding depression treatment medication alternatives.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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