Pamidronate Disodium (Pamidronate Disodium)

Prescription medicineOnly Available By Prescription

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Strength Pack Size Qty
3mg/ml vial
Pack Size
6mg/ml vial
Pack Size
9mg/ml vial
Pack Size

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Your doctor may prescribe pamidronate disodium to treat various bone disorders, including osteoporosis, high calcium levels during cancer, Paget’s disease, and bone metastases.

This medication is pivotal in restoring normal bone health by attaching to calcium phosphate crystals within the bone. Incorporating into these bone crystals, causes pamidronate to prevent bone recycling, maintaining overall bone health. Additionally, pamidronate inhibits the activity of osteoclasts, the bone cells that become overly active during cancer.


Administration of pamidronate disodium should be performed only by a trained healthcare professional through intravenous infusion, usually in an infusion clinic.

The maximum dosage per infusion is 90 mg, and the treatment frequency should not exceed every seven days.

The dosage varies based on the specific condition being treated, and adhering to your doctor’s instructions is crucial.

Your doctor may recommend calcium and vitamin D supplements between infusions.


The active ingredient in pamidronate is pamidronate disodium, and the inactive ingredients include mannitol and phosphoric acid.


There are no significant drug-drug interactions between pamidronate and other medications.


Regular dental check-ups are recommended to assess for jaw osteonecrosis.

People who are pregnant or planning to become pregnant should avoid pamidronate.

Before and during therapy, your doctor will monitor calcium, phosphate, magnesium, and potassium levels.

If you have a history of thyroid problems or kidney disease, caution is advised.

Pamidronate is excreted through the kidneys, potentially accumulating to dangerous levels in individuals with kidney disease.

Side Effects

Common adverse reactions to pamidronate may include:

  • Anemia
  • Arthralgia
  • Bone pain
  • Cough
  • Deteriorating renal function
  • Dyspnea
  • Fatigue
  • Focal segmental glomerulosclerosis
  • Hypocalcemia
  • Hypokalemia
  • Hypertension
  • Hypomagnesemia
  • Hypophosphatemia
  • Injection site disorder
  • Loss of appetite
  • Malaise
  • Myalgia
  • Nausea
  • Nephrotoxicity
  • Osteonecrosis of jaw
  • Seizure
  • Urinary tract infectious disease
  • Vomiting


Pamidronate [package insert]. Bedford, OH: Bedford Laboratories; January 2009.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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