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Orthovisc (Sodium Hyaluronate)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


ORTHOVISC is an injectable medication prescribed to treat knee pain in patients with osteoarthritis. ORTHOVISC should only be administered by a healthcare professional in an office or clinic setting.

ORTHOVISC injection works by replenishing hyaluronan in knee joints. Hyaluronan occurs naturally and acts as a lubricant to reduce painful friction when bones rub against each other during movement.

ORTHOVISC injection should only be prescribed after other options have been tried, including nonpharmacologic therapy and mild analgesics like acetaminophen.

Fact Table







Legal status


Chemical Name

Sodium Hyaluronate

Elimination half-life

3 to 5 min

Dosage (Strength)

2ml Syringe





Protein binding


PubChem CID






ATC code






Routes of administration



ORTHOVISC injection should only be injected by a licensed healthcare professional.

ORTHOVISC is injected intra-arterially into the knee once weekly for three weeks. 

Treatment for longer than three weeks has not been shown to be effective. Treating for more than one course has also not been shown to be effective.


The active ingredient in ORTHOVISC is high molecular weight ultra-pure natural hyaluronan dissolved in physiological saline. Hyaluronan occurs naturally in the body and is a glycosaminoglycan sugar.


Do not use ORTHOVISC if you have a known hypersensitivity to hyaluronan or hyaluronate preparations. 

Use ORTHOVISC with caution if you have a hypersensitivity to avian feathers, eggs, or other chicken products. ORTHOVISC is prepared using chicken combs.

ORTHOVISC should not be used in knee joints that have a skin disease or skin infection.

The knee may become temporarily inflamed after injection with ORTHVISC.

Side Effects

Some of the most common adverse reactions from ORTHVISC may include:

  • Arthralgia
  • Back Pain
  • Edema at the injection site
  • Erythema at the injection site
  • Headache
  • Pain at the injection site


  1. Orthovisc[package insert]. Woburn, MS 01801: Anika Therapeutics; 2001.
  2. Mayo Clinic, Osteoarthritis, February 20th, 2020. Retrieved April 2020.
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IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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