Orgovyx (Relugolix)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
Strength
120mg
Pack Size
Qty
What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Orgovyx (relugolix) is a prescription medication for men used to treat advanced prostate cancer. It belongs to a class of drugs called GnRH receptor antagonists, which work by lowering testosterone levels that promote the growth of prostate cancer cells. Unlike many other hormone treatments that require injections, Orgovyx is taken as an oral tablet.

Fact Table

Formula

C29H27F2N7O5S

License

US FDA

Bioavailability

Approximately 12%

Legal status

Rx-only

Chemical Name

1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea

Elimination half-life

Effective: 25 hours; terminal: 60.8 hours

Dosage (Strength)

120mg tablets; 360mg loading dose on day 1, then 120mg once daily

Pregnancy

Not indicated in females; may cause fetal harm

Brands

Orgovyx, Relumina

Protein binding

68-71%

PubChem CID

10348973

MedlinePlus

a621006

ChEBI

N/A

ATC code

L02BX04

DrugBank

DB11853

KEGG

D10888

Routes of administration

Oral

Directions

Orgovyx is taken as a once-daily tablet that patients swallow by mouth. A loading dose of 360 mg is taken on the first day. Then, the standard dosage is 120 mg taken at the same time each day, with or without food. Patients should swallow the tablet whole and not crush, chew, or break it.

Ingredients

Relugolix is the active ingredient in this drug.

Cautions

Before taking this medication, you may want to consult a healthcare provider about the following:

  • Any existing health conditions
  • Any allergies
  • A list of all medications currently being taken

Orgovyx is a treatment that lowers testosterone, which may cause changes in heart rhythm. Your doctor may monitor your heart, especially if you already take medications that affect heart rhythm.

Some people may have allergic reactions to Orgovyx, including swelling of the face, lips, or throat (angioedema). Stop taking it and seek medical care right away if this happens.

Orgovyx can harm an unborn baby. Men with female partners who can become pregnant should use reliable birth control during treatment.

Contraindications

Avoid taking this medication if there’s a known hypersensitivity or allergy to any ingredients.

Side Effects

The most common side effects of Orgovyx are hot flashes, muscle or joint pain, constipation, diarrhea, and feeling more tired than usual. Some people may also see changes in blood tests, including higher blood sugar or triglyceride levels, or lower hemoglobin, which measures red blood cells.

Orgovyx can also raise certain liver enzymes (ALT and AST), which may show stress or irritation in the liver. These changes are usually tracked with routine blood tests. Anyone who has side effects that are severe or don’t go away should talk with their healthcare provider.

References



IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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