Sign up to get notified if we do in the future.
We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Omvoh (mirikizumab-mrkz) is a humanized IgG4 monoclonal antibody that selectively targets interleukin-23 (IL-23) by binding to its p19 subunit. It is indicated for the treatment of adults with moderately to severely active ulcerative colitis (UC) who have had an inadequate response, lost response, or were intolerant to conventional therapy or biologics. By inhibiting IL-23, Omvoh reduces inflammation and promotes mucosal healing in the colon. It is the first IL-23p19 inhibitor approved for ulcerative colitis and provides a targeted immunomodulatory approach with both induction and maintenance treatment phases.
Fact Table | |
Formula | Not applicable (monoclonal antibody) |
License | US FDA (2023) |
Bioavailability | ~55% (subcutaneous) |
Legal status | Prescription only |
Chemical Name | Mirikizumab |
Elimination half-life | ~10.7 days |
Dosage (Strength) | 300 mg IV (induction); 200 mg SC every 4 weeks (maintenance) |
Pregnancy | Use only if benefits outweigh risks; no adequate human data |
Brands | Omvoh |
Protein binding | Not applicable (IgG4 monoclonal antibody) |
PubChem CID | 123823600 |
MedlinePlus | a622036 |
ChEBI | N/A |
ATC code | L04AC24 |
DrugBank | DB15090 |
KEGG | D12430 |
Routes of administration | Intravenous (IV), Subcutaneous (SC) |
Omvoh is administered in two phases:
Infusions must be given by a healthcare professional. Subcutaneous doses may be administered by a healthcare provider or self-injected after proper training. Clinical response should be assessed periodically to determine continued treatment benefit.
Each mL of Omvoh contains:
Inactive ingredients include:
Omvoh is preservative-free and must be stored refrigerated at 2°C to 8°C. Do not freeze or shake.
Omvoh is contraindicated in patients with:
Omvoh may increase the risk of infections, including upper respiratory tract infections and tuberculosis. Patients should be screened for latent TB prior to initiating therapy and monitored during treatment. Live vaccines should be avoided during treatment. As with other immunomodulators, caution is advised in patients with a history of chronic or recurrent infections, malignancy, or demyelinating disease. If a serious infection develops, Omvoh should be discontinued until resolution. Safety in pregnancy and breastfeeding has not been fully established; use only if benefits outweigh potential risks.
Common and potential side effects include: