NuvaRing (Etonogestrel/Ethinyl Estradiol)

Prescription medicineOnly Available By Prescription
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0.12mg/0.015mg
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0.12mg/0.015mg
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

NuvaRing (etonogestrel/ethinyl estradiol vaginal ring) is a vaginal ring that contains two hormones called estrogen and progestin; NuvaRing is used to prevent pregnancy in women.


Fact Table

Formula

C20H24O2

License

EU EMA

Bioavailability

38–48%

Legal status

Rx-Only

Chemical Name

Ethinylestradiol

Elimination half-life

7–36 hours

Dosage (Strength)

Ring

Pregnancy

-

Brands

NuvaRing

Protein binding

97–98%

PubChem CID

5991

MedlinePlus

a604032

ChEBI

4903

ATC code

G03CA01

DrugBank

DB00977

KEGG

D00554

Routes of administration

Vaginal (ring)

Directions

The instructions that come with your NuvaRing prescription should be followed. Read the information that comes with your prescription. Talk to your doctor if you have any questions or concerns about NuvaRing.

NuvaRing is made of a polymer containing 11.7 mg of etonogestrel and 2.7 mg of ethinyl estradiol, delivering about 0.12 mg of etonogestrel and 0.015 mg of ethinyl estradiol per day.

First, pick a comfortable position for the insertion of the NuvaRing. Compress the ring and insert it into the vagina. You may use the applicator for NuvaRing if you wish. Keep the ring in place for three weeks. Take it out at the start of the fourth week and keep it out for one week. After you take it out, place it in a foil pouch and dispose of it appropriately. Keep it out of reach from children and animals. Avoid flushing the ring in the toilet. Insert a new ring one week after the last ring was taken out, regardless of menstrual bleeding.

Ingredients

Each ring contains 11.7 mg of etonogestrel and 2.7 mg of ethinyl estradiol.

Contraindications

  • Do not use NuvaRing if you are at risk for blood clotting conditions. You may be at risk if you are older than 35 years old and smoke, currently have or have a history of a blood clot in the veins or lungs, have cerebrovascular disease, have coronary artery disease, have thrombogenic valvular or thrombogenic heart rhythm diseases, have inherited or acquired conditions in which your blood clots more than normal, have uncontrolled high blood pressure, have diabetes with vascular disease, have headaches with focal neurological symptoms, have migraines with aura, or if you have migraines and you are older than 35 years old.
  • Do not use NuvaRing if you have liver tumors.
  • Do not use NuvaRing if you have undiagnosed abnormal vaginal bleeding.
  • Do not use NuvaRing if you are pregnant.
  • Do not use NuvaRing if you have or have had breast cancer or other hormonally-sensitive cancers.
  • Do not use NuvaRing if you are allergic to any of the ingredients in the ring.
  • Do not use NuvaRing if you have Hepatitis C and take ombitasvir/paritaprevir/ritonavir with or without dasabuvir as this could cause an increase in ALT. ALT is a liver enzyme.

Cautions

WARNING: CIGARETTE SMOKING AND

SERIOUS CARDIOVASCULAR EVENTS

See full prescribing information for complete boxed warning.

  • Women over 35 years old who smoke should not use NuvaRing. 
  • Cigarette smoking increases the risk of serious cardiovascular events from combination hormonal contraceptive (CHC) use. 



  • Consult with your doctor before using NuvaRing and discuss the following:
    • Your allergies
    • Your medications
      • NuvaRing's effectiveness may be reduced or breakthrough bleeding may be increased by the use of certain medications and herbal supplements, including CYP3A4. Patients who take these medications are recommended to use back-up or a different birth control method. Ask your doctor if you are unsure whether or not you take these medications.
    • Your medical conditions
    • If you are pregnant or plan to become pregnant
    • If you are breastfeeding or plan to breastfeed
  • NuvaRing poses vascular risks and should be stopped if these occur. NuvaRing should be stopped at least 4 weeks before and continue through 2 weeks after major surgery. In women who are not breastfeeding, NuvaRing may be started 4 weeks after delivery.
  • Toxic Shock Syndrome may occur during the use of NuvaRing. Treatment should be administered if this occurs.
  • Liver problems may occur during the use of NuvaRing and should be stopped if you develop yellowing of your skin or whites of your eyes.
  • High blood pressure may occur during the use of NuvaRing. Check your blood pressure regularly. Your doctor may tell you to stop using NuvaRing if your blood pressure significantly goes up.
  • Glucose tolerance may be decreased with the use of NuvaRing. Some women may also experience changes in lipids with the use of NuvaRing and may require a different birth control method.
  • The risk of pancreatitis may be increased in women with high levels of triglycerides or a family history of high levels of triglycerides.
  • Gallbladder disease may occur or worsen with the use of NuvaRing.
  • If you have a significant change in headaches, tell your doctor. He or she may stop NuvaRing treatment.
  • Unusual vaginal bleeding may occur with the use of NuvaRing, or you may not have periods with the use of NuvaRing.

Side Effects

NuvaRing side effects include vaginal inflammation, headache, mood changes, depression, device-related events such as expulsion, discomfort, or foreign body sensation, nausea, vomiting, vaginal discharge, weight gain, vaginal discomfort, breast pain, breast discomfort, breast tenderness, painful periods, stomach pain, acne, and decreased sexual drive.

Reference:

NuvaRing (etonogestrel/ethinyl estradiol vaginal ring). Jersey City, NJ: Organon & Co.; 2022.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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