Norflex (Orphenadrine)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
100mg ER
Pack Size

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Norflex (Orphenadrine) is a muscle relaxant that helps alleviate the stiffness, pain, and discomfort caused by strains, sprains, or other injuries to muscles. It helps relax muscles in the body, providing relief and supporting recovery in combination with rest, physical therapy, and other measures.

Fact Table






Fluticasone: 1%, Salmeterol: about 4%

Legal status


Chemical Name


Elimination half-life

13–20 hours

Dosage (Strength)

100mg, 100mg ER


Consult Doctor - should be given to a pregnant woman only if clearly needed



Protein binding


PubChem CID






ATC code






Routes of administration



Follow your doctor's orders or the directions on the label. The average doses of this medicine may vary depending on your specific situation, but it's important to adhere to the prescribed dosage and schedule. Oral Norflex is typically taken as 100 mg twice daily. Swallow the tablets whole, and take the doses at the same time each day for optimal effectiveness. Consult a healthcare provider for administering Norflex injections.


Norflex contains Orphenadrine Citrate as its active ingredient.


Avoid taking or using Norflex if any of the following apply:

  • Glaucoma
  • Pyloric or duodenal obstruction
  • Stenosing peptic ulcers
  • Prostatic hypertrophy
  • Obstruction of the bladder neck
  • Cardio-spasm (megaesophagus)
  • Myasthenia gravis
  • Allergy or hypersensitivity to Norflex


  • Before starting this medication, consider discussing the following points with your healthcare professional:
    • Any other medications you're taking, as Orphenadrine can interact with other drugs, potentially increasing their effects or causing adverse reactions.
    • Existing medical conditions, which could be worsened by Orphenadrine. Ensure your doctor is aware of any neurological or gastrointestinal issues.
    • If you are pregnant or planning to become pregnant. Norflex may not be suitable during pregnancy, and your physician needs to be informed.
  • Some people may feel light-headed, dizzy, or may faint briefly after taking Norflex.
  • Norflex can affect your ability to do things that require concentration, like operating machines or driving. Be careful if you're moving around after taking it.
  • Norflex injections contain sodium bisulfite which can cause severe allergic reactions, particularly in asthmatic individuals. These reactions are rare, but more common in people with asthma.
  • If you're feeling confused, anxious, or shaky, and you're also taking painkillers like propoxyphene, there may be a risk of adverse effects. You may need to reduce the dose or stop taking one or both drugs.
  • Be cautious with Norflex if you have a fast heartbeat, heart problems, or irregular heart rhythms.
  • The safety of taking Norflex for a long time isn't known. If you're on Norflex for a while, you may need regular tests to check your blood, urine, and liver.
  • During pregnancy, Norflex should only be used if absolutely necessary, as its safety for unborn babies is uncertain.

Side Effects

Some individuals taking Norflex may experience adverse effects. Typically, these could include lightheadedness, drowsiness, fatigue, an upset stomach, nausea, constipation, and dry mouth. Norflex may also cause serious side effects that require medical attention, such as hallucinations and involuntary muscle movements. Allergic reactions to this medication could develop as rash, hives, facial or throat swelling, and trouble breathing. If side effects persist or worsen, consult a healthcare professional immediately.


  1. Norflex (Orphenadrine) Product Monograph. Northridge, CA: 3M Pharmaceuticals; 2006.
  2. Norflex (Orphenadrine) Drug Label Information. Bridgewater, NJ: Amneal Pharmaceuticals; 2019.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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