NIX 5% Dermal Cream (Permethrin)

Prescription medicineOnly Available By Prescription

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You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Nix (permethrin) 5% dermal cream is used as a topical treatment for scabies, mites that infest the skin, leading to itching and irritation.

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Elimination half-life

39.5 days

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Use Nix 5% dermal cream as prescribed by your doctor. If you have any questions or concerns about the medication, talk to your doctor or pharmacist.

Use Nix 5% dermal cream on the skin only. Avoid contact with your eyes or mouth. 

It is recommended to apply the cream from head to toe and leave it on for 8 to 14 hours before rinsing it off. If the mites don't go away, you may reapply it in 7 days.


Permethrin kills parasites like scabies and is the active ingredient in Nix 5% dermal cream.


  • Patients should not use Nix 5% dermal cream if they are allergic to its ingredients.
  • Patients younger than 2 years old should not use Nix 5% dermal cream. Before using Nix on a pediatric patient, talk to a doctor. 


  • Before using Nix 5% dermal cream, tell your doctor about:
    • All the medications you use, including other skin creams, lotions, and ointments
    • Your allergies
    • Your health problems and medical history
    • Your pregnancy or breastfeeding status
  • Itching, swelling, and redness may worsen temporarily with the use of Nix 5% dermal cream.
  • Breathing problems or an asthma attack in patients who have ragweed allergies may occur with Nix 5% dermal cream use.

Side Effects

Nix 5% dermal cream side effects include burning, stinging, or itching.

However, call your doctor if you have side effects that are bothersome or won't go away.


  1. Medscape.Permethrin

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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