Ninlaro (Ixazomib)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Ninlaro is a prescription medication indicated for the treatment of multiple myeloma, a form of blood cancer affecting plasma cells. This condition involves the abnormal proliferation of plasma cells in the bone marrow, leading to various symptoms and complications. Ninlaro is prescribed in combination with lenalidomide and dexamethasone.

Ninlaro is a proteasome inhibitor that disrupts the growth and survival of myeloma cells. By inhibiting the proteasome, a cellular structure essential for protein breakdown, Ninlaro destroys plasma cells that have become cancerous and are replicating too aggressively.


The usual directions are to take Ninlaro on days 1,8, and 15 of a 28-day chemotherapy cycle.

Take Ninlaro one hour before or two hours after meals.


The active ingredient in Ninlaro is ixazomib.


Common drug-drug interactions may include:

  • Abametapir
  • Carbamazepine
  • Clarithromycin
  • Conivaptan
  • Enzalutamide
  • Fedratinib
  • Fexinidazole
  • Fosphenytoin
  • Itraconazole
  • Mavacamten
  • Mitotane
  • Omaveloxolone
  • Phenobarbital
  • Phenytoin
  • Primidone
  • Rifampin
  • St John's Wort


Your doctor should monitor your platelet count and at each dose adjustment while taking this medication.

Tell your doctor if you experience severe gastrointestinal side effects like diarrhea, nausea, vomiting, or constipation.

Tell your doctor if you experience pain, numbness, or tingling in your hands or feet during treatment.

Tell your doctor if you have a history of kidney or liver problems before starting this drug.

Tell your healthcare provider if you experience a rash after starting Ninlaro.

Do not take this drug if you are pregnant or trying to become pregnant.

Side Effects

Common adverse reactions to this drug are:

  • Bronchitis
  • Cholestatic hepatitis
  • Constipation
  • Diarrhea
  • Disorder of eye
  • Hepatocellular liver damage
  • Hepatotoxicity
  • Hemolytic uremic syndrome, Thrombocytopenia, Grade 3 or 4
  • Injury of liver
  • Nausea
  • Neutropenia, All Grades
  • Peripheral edema
  • Peripheral nerve disease
  • Rash
  • Stevens-Johnson syndrome
  • Steatosis of liver
  • Thrombocytopenia, All Grades
  • Thrombotic thrombocytopenic purpura
  • Vomiting


Ninlaro [package insert]. Lexington, MA: Takeda; May 2022.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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