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Nexlizet (Bempedoic acid and Ezetimibe)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Nexlizet (bempedoic acid and ezetimibe) is used with diet and statin therapy to treat adults with heterozygous familial hypercholesterolemia or atherosclerotic cardiovascular disease who need extra lowering of low-density lipoprotein cholesterol (LDL-C). 

Fact Table




US DailyMed, EU EMA



Legal status


Chemical Name

Bempedoic acid

Elimination half-life

21±11 hrs

Dosage (Strength)






Protein binding


PubChem CID






ATC code






Routes of administration

By mouth


Nexlizet comes in an oral tablet containing 180 mg of bempedoic acid and 10 mg of ezetimibe. 

You should take one tablet by mouth one time a day with or without food. 

Do not crush or chew the tablet; it should be swallowed whole. 

If you are also taking bile acid sequestrants, take Nexlizet at least 2 hours before or 4 hours after taking bile acid sequestrants.


Bempedoic acid and ezetimibe are the active ingredients in Nexlizet. 


Avoid taking Nexlizet if you have any allergy to ezetimibe or any of the other ingredients contained in Nexlizet.


  • Before you begin treatment with Nexlizet, discuss the following with your doctor:
    • If you take any medications. These include prescription and nonprescription medications, vitamins, and herbal supplements. You should not take Nexlizet with simvastatin more than 20 mg or pravastatin more than 40 mg.
    • If you have any allergies.
    • If you have any medical conditions.
    • If you are currently pregnant or plan to become pregnant.
    • If you are currently breastfeeding or plan to breastfeed.
  • An increase in uric acid levels in the blood which can lead to gout can be caused by Nexlizet.
  • Tendon rupture can be caused by Nexlizet. Immediately tell your doctor if you develop pain, swelling, or inflammation of your joints. 

Side Effects

Upper respiratory tract infection, the flu, bronchitis, stomach pain, back pain, joint pain, extremity pain, anemia, increased liver enzymes, diarrhea, tiredness, sinusitis, muscle spasms, and increased uric acid levels in the blood are common side effects of Nexlizet. However, these may not be all the side effects that can be caused by Nexlizet.

Immediately speak to your doctor if you experience troublesome or persistent side effects.


Nexlizet. Ann Arbor, MI: Esperion Therapeutics, Inc.; 2021.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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