Nexletol (bempedoic acid)

Prescription medicineOnly Available By Prescription
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Strength Pack Size Qty
Strength
180mg
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Top Generic choice

Strength Pack Size Qty
Strength
180mg
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Qty

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Nexletol (bempedoic acid) is for treating adults with heterozygous familial hypercholesterolemia or atherosclerotic cardiovascular disease who need extra lowering of low-density lipoprotein cholesterol (LDL-C). It is used with diet and statin therapy.


Fact Table

Formula

C19H36O5

License

US DailyMed, EU EMA

Bioavailability

-

Legal status

Rx-only

Chemical Name

Bempedoic acid

Elimination half-life

21±11 hrs

Dosage (Strength)

180mg

Pregnancy

Consult Doctor

Brands

Nexletol

Protein binding

99.3%

PubChem CID

10472693

MedlinePlus

a620020

ChEBI

149601

ATC code

N02CD06

DrugBank

DB12457

KEGG

C10AX15

Routes of administration

By mouth

Directions

Nexletol comes in a 180 mg tablet.

You should take one tablet by mouth one time a day with or without food.

Ingredients

Bempedoic acid is the active ingredient in Nexletol.

Cautions

  • Before you begin treatment with Nexletol, tell your doctor:
    • If you take any medications; these include prescription and nonprescription medications, vitamins, and herbal supplements. You should avoid taking Nexletol with simvastatin doses of 20 mg or more and pravastatin doses of 40 mg or more.
    • If you have any allergies.
    • If you have any health conditions.
    • If you are currently pregnant or plan to become pregnant.
    • If you are currently breastfeeding or plan to breastfeed.
  • Increased uric acid levels in the blood that can lead to gout can be caused by taking Nexletol.
  • Tendon rupture can be caused by Nexletol. You should stop taking Nexletol and immediately talk to your doctor if you develop joint pain, swelling, or inflammation

Side Effects

Upper respiratory tract infection, muscle spasms, stomach pain, back pain, bronchitis, pain in extremity, anemia, and increased liver enzymes are some of the most common side effects of Nexletol.

These are not all of the possible side effects of Nexletol. Immediately talk to your doctor if you develop troublesome or continuous side effects.

Reference:

Nexletol. Ann Arbor, MI: Esperion Therapeutics, Inc.; 2021.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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