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Neupro Transdermal Patch (Rotigotine)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
1mg/24 hours
Pack Size
2mg/24 hours
Pack Size
3mg/24 hours
Pack Size
4mg/24 hours
Pack Size
6mg/24 hours
Pack Size
8mg/24 hours
Pack Size

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Neupro (rotigotine transdermal system) is a patch that is medicated with a dopamine agonist for the treatment of Parkinson's disease (PD) and moderate-to-severe primary Restless Legs Syndrome (RLS). 

Parkinson's disease is a degenerative nervous system disorder associated with decreased levels of dopamine in the brain, causing tremors, difficulty moving, stiff muscles, and problems with balance.

Restless Legs Syndrome is a disorder that causes you to feel a sudden urge to move your legs because of uncomfortable aching or tugging sensations. 

Fact Table




US DailyMed, EU EMA



Legal status


Chemical Name


Elimination half-life

5–7 hours

Dosage (Strength)

1mg - 8mg (24 hours patches)


Consult Doctor



Protein binding


PubChem CID






ATC code






Routes of administration

Transdermal patch


Parkinson's disease

Neupro (rotigotine transdermal system) dosages can range from 2 mg/24 hours to 8 mg/24 hours.

Restless Legs Syndrome

Neupro (rotigotine transdermal system) dosages can range from 1 mg/24 hours to 3 mg/24 hours.

Once you are prescribed and buy medication neupro patch, then the Neupro patch should be applied to the skin once a day at around the same time each day. The sticky side should be placed on clean, dry skin on the front of the abdomen, flank, hip, shoulder, thigh, or upper arm. The skin site where you will be placing the patch should not be hairy, oily, irritated, or scratched. You should avoid placing the patch where it will be rubbed by clothing. 

The patch should be held firmly in place for 30 seconds to ensure that it sticks well. Place the patch at a different site each day (for instance, from the left side to the right side or from the lower body to the upper body). 

Do not apply the patch to the same site more than once every 14 days. Your prescribed dose may require one or more patches.


The active ingredient in the Neupro transdermal patch is Rotigotine. Rotigotine is a dopamine agonist.


Before you start using Neupro (rotigotine transdermal system), you should tell your doctor about any medications you take, including prescription, over-the-counter, vitamins, and supplements. 

Neupro may not be right for everyone. Before you start using Neupro (rotigotine transdermal system), be sure to tell your doctor if you:

  • have trouble breathing.
  • have a sleep disorder or daytime sleepiness.
  • have mental disorders like schizophrenia, bipolar disorder, or psychosis.
  • feel unwell when you stand up.
  • drink alcohol.
  • have blood pressure problems.
  • currently have heart problems or have a history of heart problems.
  • are pregnant or intend to become pregnant. 
  • are breastfeeding or intend to breastfeed.

Before you start using Neupro, be sure to discuss your allergies with your doctor. Neupro contains sodium metabisulfite that can cause allergic reactions in people who have a sulfite sensitivity. Neupro may also contain other ingredients that can cause an allergic reaction. 

Falling asleep or drowsiness during daily activities, including while driving, may occur.

 Do not drive, operate machinery, or work at heights until you know how Neupro affects you.

Hallucinations, psychosis, or involuntary movements may occur while using Neupro.

A symptomatic drop in blood pressure when sitting or standing up may occur with the use of Neupro, especially during dosage increases. Fainting may also occur.

An increase in blood pressure or heart rate may occur during treatment with Neupro and should be taken into account if you have cardiovascular disease.

Reactions at the application site can develop and may be severe. Be sure to rotate the Neupro patch application site each day.

If you experience uncontrollable urges or behaviors while using Neupro, let your doctor know immediately. Your doctor may decrease your dose or discontinue Neupro.

If you stop Neupro or decrease the dose all of a sudden, you may experience a very high fever and confusion. It is recommended to gradually decrease the dose.

Let your doctor know if you experience withdrawal symptoms such as anxiety, depression, tiredness, trouble sleeping, sweating, and pain. These symptoms may occur during dosage decreases or after stopping Neupro.

If you must have magnetic resonance imaging (MRI) or a cardioversion, be sure to take off your Neupro transdermal patch prior to the procedure. These procedures can burn the skin where the Neupro is applied.

Side Effects

As with any medication, Neupro can have side effects. If you experience any side effects while using Neupro for Parkinson's, be sure to speak with your doctor. Common side effects of Neupro include:

  • Skin reactions at the application site
  • Anorexia
  • Dizziness
  • Drowsiness/sleepiness
  • Excessive sweating
  • Headache
  • Involuntary movements
  • Nausea
  • Swelling of hands or legs
  • Problems with sleep
  • Problems with vision
  • Vomiting

Be sure to keep Neupro away from children and pets. Be sure to read the Instructions for Use before you apply and remove the patch.


  1. NEUPRO Prescribing Information. Smyrna, GA: UCB, Inc., 2021.
  2. What Is Parkinson's? Parkinson's Foundation. Accessed October 26, 2021.
  3. Restless Legs Syndrome. Cleveland Clinic. Last reviewed January 24, 2020. Accessed October 26, 2021.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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