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Mytesi (Crofelemer)

Prescription medicineOnly Available By Prescription
Sezzle

Top brand choice

Strength Pack Size Qty
Strength
125mg
Pack Size
Qty

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Some people with Human Immunodeficiency Virus (HIV) go on to develop Acquired Immunodeficiency Syndrome (AIDS). Treating this condition requires a combination of drugs, including antiretroviral medications. 

Mytesi's mechanism of action is blocking two proteins in the intestines called cyclic adenosine monophosphate (cAMP)-stimulated cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion channel. It also blocks calcium-activated chloride ion channels in the enterocyte luminal membrane.

Mytesi is an anti-diarrheal medication that stops the side effects of antiretrovirals in the gut. It should only be given to people who have confirmed diarrhea that is not caused by a virus, bacteria, or fungus.

Fact Table

Formula

(C15O6,7H12)n

License

US FDA

Bioavailability

Little or no absorption from the gut

Legal status

AU, US: Rx Only

Chemical Name

Crofelemer

Elimination half-life

Not Determined

Dosage (Strength)

125mg

Pregnancy

No Known Risks

Brands

Mytesi

Protein binding

-

PubChem CID

347909853

MedlinePlus

a613016

ChEBI

-

ATC code

A07XA06

DrugBank

DB04941

KEGG

D03605

Routes of administration

By mouth

Directions

Take Mytesi 125 mg twice daily with or without food. The capsules have a coating and should not be crushed or chewed as it may affect the absorption of the drug. 

Ingredients

The active ingredient in Mytesi is crofelemer. Do not crush or chew this capsule before taking it.

Interactions

There are no known significant drug-drug interactions with this Mystesi.

Mytesi capsules are stored at room temperature.

Cautions

Before starting Myesi, your doctor or healthcare professional should confirm that your diarrhea is not from a bacterial, viral, or fungal infection.

Tell your doctor if you have a history of liver problems while taking this drug. 

Side Effects

Some of the most common adverse reactions to this drug may include the following:

  • Abdominal distension
  • Abdominal pain
  • Acne vulgaris
  • Anxiety
  • Constipation
  • Cough
  • Decreased white blood cell count
  • Depression
  • Dermatitis
  • Dizziness
  • Dyspepsia
  • Flatulence
  • Gastroenteritis
  • Giardiasis
  • Hemorrhoids
  • Herpes zoster
  • Increased liver enzymes
  • Nausea
  • Nephrolithiasis
  • Pollakiuria
  • Sinusitis
  • Urinary tract infection
  • Xerostomia

Tell your doctor and pharmacist about any of the above side effects.

References

Mytesi. San Francisco, CA: Napo Pharmaceuticals; 2018.


IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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