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Minolira (Minocycline hydrochloride)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


MinoLira (Minocycline Hydrochloride) is a tetracycline medication used by patients over the age of 12 to treat inflammatory pimples and red bumps of moderate to severe acne vulgaris. 

Fact Table




US FDA, US DailyMed



Legal status


Chemical Name


Elimination half-life


Dosage (Strength)

105mg, 135mg


Consult Doctor



Protein binding


PubChem CID






ATC code






Routes of administration

By mouth


MinoLira comes in 105 mg and 135 mg scored extended-release tablets.

One mg per kg body weight by mouth once daily for 12 weeks is the recommended dose.

The dose may need to be adjusted in patients who have kidney problems.


Minocycline Hydrochloride is contained in each extended-release tablet.


Do not take MinoLira if you have allergies to other tetracycline medications.


  • Before you start taking MinoLira, tell your doctor:
    • If you have any allergies
    • About any medications you may take, including prescription and nonprescription medications, vitamins, and herbal supplements
    • If you have any medical conditions, including liver or kidney complications
    • If you are pregnant or plan to become pregnant
    • If you are breastfeeding or plan to breastfeed
  • Permanent teeth discoloration in infants and children during tooth development can be caused by MinoLira.
  • Severe irritation/inflammation and bleeding in the colon can be due to MinoLira. Immediately tell your doctor if you experience watery diarrhea, persistent diarrhea, or blood in stools.
  • Feeling dizzy or lightheaded can be a result of taking MinoLira. You should avoid driving or operating machinery until you know how you are affected by MinoLira.
  • Sensitivity of the skin when exposed to sunlight can be an effect of MinoLira. You should protect your skin while taking MinoLira and avoid using sunlamps or tanning beds.
  • Intracranial hypertension can be caused by taking MinoLira. Discontinue use if symptoms develop.
  • Autoimmune problems can be caused by MinoLira.
  • Serious allergic and skin reactions can be a result of using MinoLira. Discontinue use if you develop a rash or other symptoms. Immediately get medical attention if you start having trouble breathing, swelling of the lips, mouth, or throat, hives, or any other severe symptoms.

Side Effects

Dizziness, fatigue, headache, and itchy skin are the most common side effects of MinoLira. 

Immediately talk to your doctor if you experience persistent or worsening side effects.


  1. MinoLira Prescribing Information. Charleston, SC: EPI Health, LLC
  2. MinoLira Important Safety Information. Accessed February 6, 2022.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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