Canada Drugs Direct

Visiting from Canada?

Want to save up to 80% on your medications? Signup below to be notified if we open a Canadian Online Pharmacy.

I agree to receive email updates from Canada Drugs Direct

Looking for Call us toll free 1-800-500-2897

Megace (Megestrol)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

Top Generic choice

Strength Pack Size Qty
Pack Size
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


MEGACE (megestrol) is a prescription medication used to treat several different conditions. It can be prescribed for:

  • Anorexia or cachexia associated with AIDS
  • Cancer-related cachexia
  • Breast cancer
  • Endometrial cancer

MEGACE is a synthetic progesterone that mimics normal hormones that are present in the body. It stimulates appetites by reducing the effects of hormones that make the body feel "full". It treats cancer by decreasing the amount of luteinizing hormone available to endometrial and breast cancers. Luteinizing hormone may contribute to the growth of these types of cancers.

Fact Table







Legal status


Chemical Name


Elimination half-life

34 hours

Dosage (Strength)



Consult Doctor



Protein binding


PubChem CID






ATC code






Routes of administration

By mouth


Take MEGACE exactly as prescribed by your doctor. The normal MEGACE dose depends on what is being treated:

  • Anorexia or cachexia associated with AIDS: 625-800 mg of MEGACE suspension by mouth once daily
  • Breast cancer: 40 mg of MEGACE tablets by mouth four times daily for two months.
  • Cancer-related cachexia: 160 to 800 mg of MEGACE tablet by mouth every day in divided doses
  • Endometrial cancer: 40 to 320 mg of MEGACE tablet by mouth in divided doses for two months.

If you are taking MEGACE for a cancer diagnosis, take it exactly as prescribed by your oncologist.


The active ingredient in MEGACE is megestrol.


Common drug-drug interactions with MEGACE may include:

  • Anticoagulants
  • Dofetilide
  • Pomalidomide
  • Ulipristal


Tell your doctor if you have a history of Cushing syndrome. Some people have developed Cushing syndrome with long-term use.

Tell your doctor if you have a history of diabetes.

Tell your doctor if you have a history of thromboembolism.

Side Effects

The most common side effects of MEGACE include:

  • Abdominal pain
  • Albuminuria
  • Alopecia
  • Candidiasis
  • Cough
  • Decreased libido
  • Diarrhea
  • Dyspepsia
  • Edema
  • Fever
  • Flatulence
  • Gynecomastia
  • Headache
  • Hyeprtension
  • Hyperglycemia
  • Impotence
  • Insomnia
  • Nausea
  • Pain
  • Palpitations
  • Skin rash
  • Urinary incontinence
  • Urinary tract infection
  • Vomiting
  • Weakness

Buy MEGACE from Canada Drugs Direct with a valid prescription from your doctor. Search for the best MEGACE cost on Canada Drugs Direct.


Megace [package insert]. Princeton, New Jersey: Bristol-Myers Squibb; 2012.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

product-reviews Product Reviews