Only Available By Prescription
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| Strength | Pack Size | Qty | |
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Strength
0.5% 10ml Polyamp Steripack
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Strength
0.5% 20ml single-use vials
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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Marcaine (bupivacaine hydrochloride injection, USP) is a long-acting local anesthetic indicated for local or regional anesthesia, including epidural, caudal, and peripheral nerve blocks, as well as infiltration anesthesia in surgical, dental, and obstetric procedures. Bupivacaine blocks nerve impulse transmission by inhibiting sodium ion influx through voltage-gated sodium channels. Marcaine is valued for its prolonged duration of action, often exceeding that of lidocaine or mepivacaine, making it especially suitable for extended surgical procedures and postoperative pain management.
| Fact Table | |
| Formula | C18H28N2O·HCl |
| License | US FDA; EMA |
| Bioavailability | Not applicable (local administration); systemic absorption depends on site and dose |
| Legal status | Prescription only |
| Chemical Name | 1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide hydrochloride |
| Elimination half-life | ~2.7 hours (adults); up to 8.1 hours (neonates) |
| Dosage (Strength) | 0.25%, 0.5%, 0.75% solutions (with/without epinephrine) |
| Pregnancy | Category C – use only if clearly needed |
| Brands | Marcaine, Sensorcaine, Vivacaine, generic bupivacaine |
| Protein binding | ~95% |
| PubChem CID | 2474 |
| MedlinePlus | a682621 |
| ChEBI | CHEBI:3198 |
| ATC code | N01BB01 |
| DrugBank | DB00297 |
| KEGG | D07594 |
| Routes of administration | Epidural, spinal, infiltration, peripheral nerve block |
Marcaine must be administered by trained healthcare professionals experienced in regional anesthesia techniques.
Do not inject intravenously. Always aspirate before injection to avoid intravascular administration.
Each mL of Marcaine contains:
Other components:
Preservative-free formulations are used for spinal and certain epidural applications.
Marcaine is contraindicated in:
Accidental intravascular or intrathecal injection can cause severe cardiovascular and CNS toxicity, including seizures, hypotension, arrhythmias, and cardiac arrest. Use with caution in patients with cardiovascular disease, hepatic impairment, elderly, or debilitated patients. Ensure resuscitative equipment and personnel are immediately available. Do not mix with other local anesthetics unless compatibility is known. Use preservative-free solutions for intrathecal administration only.
Potential adverse effects include:
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If you have any questions at all, or would like to place an order, you are encouraged to contact us by toll-free
phone 1-888-904-8467 or email info@canadadrugsdirect.com.
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Canada Drugs Direct employs dedicated, professional licensed pharmacists to ensure that each and every order is reviewed before it is dispensed for the safety and health of our customers. At CanadaDrugsDirect.com, your health is our top priority.
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