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Lotemax SM (loteprednol etabonate ophthalmic gel)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
3.8mg 5g
Pack Size

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Lotemax SM (Loteprednol Etabonate Ophthalmic Gel) 0.38% is used to treat eye inflammation and pain after eye surgery. It is a corticosteroid. 

Fact Table







Legal status


Chemical Name


Elimination half-life

2.8 hrs

Dosage (Strength)

3.8mg 5g


Consult Doctor


Lotemax SM

Protein binding


PubChem CID






ATC code






Routes of administration

Eye drops


Lotemax SM should only be used in the eye. It is a sterile preserved gel.

You should turn the closed bottle upside down and shake once to fill the tip before placing the gel into the eye(s).

Beginning the day after surgery, place one drop into the affected eye(s) three times a day for 14 days. 


There is 3.8 mg of Loteprednol Etabonate in each gram of gel. 


If you have a viral eye disease or a bacterial or fungal eye infection, avoid using Lotemax SM.


  • Before you begin using Lotemax SM eye gel, let your doctor know:
    • If you have any allergies
    • About all medications you may take, including other eye drops or eye gels
    • If you have any medical conditions
    • If you are currently pregnant or plan to become pregnant
    • If you are currently breastfeeding or plan to breastfeed
  • Your risk for glaucoma or other vision problems can be increased by using Lotemax SM for a long time. If you use Lotemax SM for more than 10 days, your intraocular pressure should be checked.
  • Inform your doctor if you have cataracts.
  • Prolonged healing time may result from using Lotemax SM. The risk for bleb formation after cataract surgery can be increased by Lotemax SM. 
  • The risk for secondary eye infections can be increased by using Lotemax SM for a long time. It can mask or worsen active purulent infections.
  • The use of Lotemax SM for an extended period of time can extend the course of or worsen the symptoms of viral eye infections, including herpes simplex.
  • Your risk for fungal eye infections can be increased by using Lotemax SM for a long time. 
  • When your eyes are inflamed or irritated, do not wear contact lenses.

Side Effects

Blurry vision, light sensitivity, eye swelling, or eye redness are the most common side effects of Lotemax SM. 

Immediately tell your doctor if you experience troublesome or continuous side effects.


  1. Lotemax SM Prescribing Information. Tampa, FL: Bausch & Lomb Incorporated; 2020.
  2. Loteprednol (Ophthalmic Route). Mayo Clinic. Last updated May 1, 2021. Accessed February 6, 2022.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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