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Lopressor (Metoprolol Tartrate)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Lopressor can be prescribed for any of the following:

  • Hypertension
  • Angina
  • Atrial fibrillation
  • Heart Failure
  • Migraine
  • Heart Attack
  • Heart arrhythmias

Lopressor works by reducing the workload on the heart and blood vessels.

Fact Table







Legal status


Chemical Name


Elimination half-life

3–7 hours

Dosage (Strength)

25mg, 37.5mg, 50mg, 75mg, 100mg


Consult Doctor


Lopressor, Metolar XR

Protein binding


PubChem CID






ATC code






Routes of administration

By mouth


The dosage varies from 25-400 mg by mouth once daily. Take Lopressor exactly as prescribed.


The active ingredient in Lopressor is metoprolol.


The most common drug-drug interactions include:

  • Acetylcholinesterase Inhibitors
  • Ajmaline
  • Alfuzosin
  • Alpha1-Blockers
  • Alpha2-Agonists
  • Amifostine
  • Amiodarone
  • Amphetamines
  • Antidiabetic Agents
  • Antipsychotic Agents
  • Artemether and Lumefantrine
  • Barbiturates
  • Benperidol
  • Beta2-Agonists
  • Bradycardia-Causing Agents
  • Brigatinib
  • Brimonidine
  • Bromperidol
  • Bupivacaine
  • Cannabis
  • Ceritinib
  • Cholinergic Agonists
  • CYP2D6 Inhibitors 
  • Dexmethylphenidate
  • Diazoxide
  • Dipyridamole
  • Disopyramide
  • DOBUTamine
  • Dronedarone
  • DULoxetine
  • EPHEDrine
  • EPINEPHrine
  • Ergot Derivatives
  • Etofylline
  • Fexinidazole
  • Fingolimod
  • Flunarizine
  • Grass Pollen Allergen Extract
  • Herbal Products with Blood Pressure Increasing Effects
  • Herbal Products with Blood Pressure Lowering Effects
  • Hydroxychloroquine
  • Hypotension-Associated Agents
  • Ivabradine
  • Lacosamide
  • Lercanidipine
  • Levodopa-Containing Products
  • Lidocaine 
  • Lormetazepam
  • Mavacamten
  • Mepivacaine
  • Methacholine
  • Methoxyflurane
  • Methylphenidate
  • Midodrine
  • Mirabegron
  • Molsidomine
  • Naftopidil
  • Nicergoline
  • Nicorandil
  • NIFEdipine
  • Nitroprusside
  • Nonsteroidal Anti-Inflammatory Agents
  • Obinutuzumab
  • Ozanimod
  • Peginterferon Alfa-2b
  • PENTobarbital
  • Pentoxifylline
  • Pholcodine
  • Phosphodiesterase 5 Inhibitors
  • Ponesimod
  • Prostacyclin Analogues
  • Quinagolide
  • Reserpine
  • RifAMPin
  • Rivastigmine
  • Siponimod
  • Succinylcholine
  • Sulfonylureas
  • Tasimelteon
  • Terlipressin
  • Theophylline Derivatives
  • Tofacitinib
  • White Birch Allergen Extract


Tell your doctor if you have a history of diabetes, heart failure, or liver problems. 

Ask your doctor and pharmacist for a full list of side effects before starting Lopressor.

Side Effects

Common side effects may include:

  • Abdominal Pain
  • Accidental Injury
  • Alopecia
  • Anxiety
  • Arterial Insufficiency
  • Arthralgia
  • Arthritis
  • Arthropathy
  • Bradycardia
  • Bronchospasm
  • Bullous Pemphigoid
  • Cerebrovascular Accident
  • Chest Pain
  • Claudication
  • Cold Extremity
  • Confusion
  • Constipation
  • Decreased HDL Cholesterol
  • Decreased Libido
  • Depression
  • Diaphoresis
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Dyspnea
  • Erectile Dysfunction
  • Erythroderma
  • Exacerbation of Psoriasis
  • Fatigue
  • First-Degree Atrioventricular Block
  • Flatulence
  • Gangrene of Skin and/or Subcutaneous Tissues
  • Hallucination
  • Headache
  • Heart Failure
  • Heartburn
  • Hepatic Insufficiency
  • Hepatitis
  • Hypotension
  • Impotence
  • Increased Serum Alkaline Phosphatase
  • Increased Serum Transaminases
  • Increased Serum Triglycerides
  • Insomnia
  • Jaundice
  • Lichenoid Dermatitis
  • Musculoskeletal Pain
  • Nausea
  • Nervousness
  • Nightmares
  • Palpitations
  • Paresthesia
  • Pemphigoid-Like Lesion
  • Peripheral Edema
  • Peyronie Disease
  • Pruritus
  • Retroperitoneal Fibrosis
  • Rhinitis
  • Skin Rash
  • Sleep Disturbance
  • Stomach Pain
  • Syncope
  • Temporary Amnesia
  • Tinnitus
  • Unstable Diabetes
  • Vertigo
  • Visual Disturbance
  • Vomiting
  • Weight Gain
  • Wheezing
  • Xerostomia


Lopressor [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corp.; 2008.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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