Lidex Cream (Fluocinonide) (Lyderm in Canada)

Prescription medicineOnly Available By Prescription

Top Generic choice

Strength Pack Size Qty
0.05% 25g
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


LIDEX cream (fluocinonide) is a topical prescription that is prescribed for inflammatory and pruritic dermatologic conditions.

The most common conditions treated with LIDEX include atopic dermatitis, psoriasis, and other inflammatory skin conditions. 

LIDEX is commonly prescribed by primary care physicians and dermatologists.

LIDEX is a corticosteroid cream and it works by suppressing the immune response where it's applied.


The standard LIDEX cream dosage is to apply to the affected area(s) two to four times daily as directed by the physician.

Do not use for more than fourteen days in a row. Call your doctor if there is no improvement during this time.

Do not wrap a dressing over the medication after applying it.


Fluocinonide is the active ingredient in LIDEX.

The inactive ingredient list includes:

  • 1,2,6-hexanetriol
  • Cetyl alcohol
  • Citric acid monohydrate
  • Mineral oil
  • Propylene glycol
  • Stearyl alcohol


LIDEX is a topical medication, so it has very few drug interactions. It should not be used with aldesleukin.


It is rare for the medication to absorb into the bloodstream, but can happen with prolonged usage. Use caution if applying LIDEX cream to open skin.

LIDEX cream may increase the risk of skin infections during use.

Side Effects

Side effects from LIDEX are more common when using for greater than 2 weeks or if a dressing is applied over the cream.

Common side effects can include:

  • Acneiform eruptions
  • Allergic contact dermatitis
  • Burning
  • Dryness
  • Folliculitis
  • Hypertrichosis
  • Hypopigmentation
  • Irritation
  • Itching
  • Maceration of the skin
  • Miliaria
  • Perioral dermatitis
  • Secondary infection
  • Skin Atrophy
  • Striae


IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

product-reviews Product Reviews