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Lexiva (Fosamprenavir)

Also Known as Telzir

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


LEXIVA is a prescription medication that treated HIV infection. It should be used in combination with other antivirals in the treatment of HIV infection.

LEXIVA is an HIV protease inhibitor. It works by blocking the function of a critical protein HIV-1 protease. By blocking protease, LEXIVA prevents HIV viral particles from replicating.


Take each LEXIVA dosage with or without food.

Take LEXIVA exactly as prescribed by the doctor. The dose varies greatly depending on different patient factors:

  • Hepatic impairment: Adjusted based on directions from the prescriber
  • Treatment-naive: LEXIVA 1400 mg by mouth twice daily plus ritonavir
  • Pediatric (2 to 18 years old): Calculate based on body weight
  • Protease Inhibitor-experienced adults: LEXIVA 700 mg twice daily plus ritonavir 100 mg twice daily

The doctor must carefully monitor treatment while taking LEXICA. The dose should not be skipped or changed without directions from the doctor.


The active ingredient in LEXIVA is fosamprenavir.


LEXIVA is CONTRAINDICATED with the following medications:

  • Cisapride
  • Delavirdine
  • Dihydroergotamine
  • Ergonovine
  • Ergotamine
  • Flecainide
  • Lovastatin
  • Methylergonovine
  • Midazolam
  • Pimozide
  • Propafenone
  • Rifampin
  • Simvastatin
  • St. John's Wort
  • Triazolam

LEXIVA has the potential for many drug-drug interactions. Tell your doctor and pharmacist every medication you are taking before you start LEXIVA. Use caution when taking the following drugs:

  • Alprazolam
  • Amiodarone
  • Atazanavir
  • Atorvastatin
  • Bepridil
  • Calcium Channel Blockers
  • Carbamazepine
  • Clorazepate
  • Cyclosporine
  • Dexamethasone
  • Diazepam
  • Efavirenz
  • Flurazepam
  • Fluticasone
  • H2 receptor antagonists
  • Indinavir
  • Itraconazole
  • Ketoconazole
  • Lidocaine
  • Lopinavir/ritonavir
  • Methadone
  • Nelfinavir
  • Nevirapine
  • Oral contraceptives
  • Paroxetine
  • PDE5 Inhibitors
  • Phenobarbital
  • Phenytoin
  • Proton pump inhibitors
  • Quinidine
  • Rapamycin
  • Rifabutin
  • Rosuvastatin
  • Saquinavir
  • Tacrolimus
  • Trazodone
  • Tricyclic antidepressants
  • Warfarin


LEXIVA can cause serious skin conditions like Stevens-Johnson syndrome. 

Tell your doctor if you have a history of sulfonamide allergy, hepatitis B, or hepatitis C.

While taking LEXIVA, some people develop metabolic disorders like diabetes mellitus, redistribution of body fat, and high cholesterol.

LEXIVA may increase the risk of anemia or bleeding in people with hemophilia.

Side Effects

Common side effects of LEXIVA include:

  • Diarrhea
  • Headache
  • Nausea
  • Rash
  • Vomiting


Lexiva [package insert]. Research Triangle Park, NJ: GlaxoSmithKline; 2009.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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