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Kynmobi (Apomorphine HCI) Sublingual film

Prescription medicineOnly Available By Prescription

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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Kynmobi (apomorphine hydrochloride) is a dissolvable film that is placed under the tongue for the treatment of short-term, intermittent “off” episodes in patients who have Parkinson's Disease.

Fact Table




US DailyMed



Legal status


Chemical Name

Apomorphine HCI

Elimination half-life

40 minutes

Dosage (Strength)

10mg - 50mg


Consult Doctor



Protein binding


PubChem CID






ATC code






Routes of administration

Subcutaneous injection


Follow your prescription's instructions. Talk to your doctor or pharmacist about any questions or concerns you may have about your Kynmobi prescription. Your doctor may prescribe a medication to help prevent nausea and vomiting associated with Kynmobi treatment.

Kynmobi is available in 10 mg, 15 mg, 20 mg, 25 mg, and 30 mg sublingual films. 

The Kynmobi film should be placed under the tongue to dissolve. Do not cut, chew, or swallow the films. 

The general dose is between 10 mg and 30 mg per dose as needed. You should wait at least 2 hours between doses before administering another dose. Do not take more than 5 doses a day. Do not take more than 30 mg at one time.


The active ingredient contained in Kynmobi is apomorphine hydrochloride, a non-ergoline dopamine agonist.


Avoid taking Kynmobi with 5HT3 antagonists such as ondansetron, granisetron, dolasetron, palonosetron, and alosetron. If you do not know whether or not you take 5HT3 antagonists, ask your doctor. 

Avoid taking Kynmobi if you have an allergy to apomorphine, sodium metabisulfite, or any of Kynmobi's other ingredients or excipients.


  • Before you start treatment with Kynmobi, inform your doctor:
    • Of all the medications you take, including prescription, over-the-counter, vitamins, and herbal supplements
    • Of your allergies
    • Of your medical conditions
    • Of your alcohol consumption
    • If you are pregnant or plan to become pregnant
    • If you are breastfeeding or plan to breastfeed 
  • Nausea and vomiting can occur with the use of Kynmobi.
  • Drowsiness or falling asleep, even during the daytime, can occur with the use of Kynmobi. Avoid driving and operating machinery until you know how you are affected by the medication.
  • Low blood pressure can occur with the use of Kynmobi. Be sure to monitor your blood pressure during treatment with Kynmobi.
  • Irritation to the inside of your mouth can occur with the use of Kynmobi. If this occurs, let your doctor know as he or she may pause or stop your treatment.
  • Your risk for falls may be greater with the use of Kynmobi.
  • Hallucinations and psychosis can occur with the use of Kynmobi. Immediately contact your doctor if you experience these effects.
  • Impulsive behaviors can occur with the use of Kynmobi. Immediately contact your doctor if you develop impulsive behaviors or intense urges to gamble, spend money, or other urges.
  • Withdrawal-emergent and confusion with symptoms such as fever, muscle stiffness, altered mental status, autonomic instability, and increased serum creatine kinase levels can occur if Kynmobi is suddenly discontinued or the dose is suddenly decreased. Withdrawal should be gradual and doses should be tapered. 
  • QTc prolongation that can lead to torsades de pointes or death can occur with the use of Kynmobi. Discuss risk factors with your doctor before starting treatment with Kynmobi.

Side Effects

Dizziness, drowsiness, nausea, and mouth irritation, pain, and tingling are the most common side effects of Kynmobi. However, other side effects can occur with Kynmobi. Immediately call your doctor if you have side effects that bother you or continue.


Kynmobi (apomorphine hydrochloride) sublingual film. Marlborough, MA: Sunovion Pharmaceuticals Inc.; 2020.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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