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Klisyri (Tirbanibulin Ointment)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
1% Ointment (each packet is 0.25g)
Pack Size

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Klisyri (tirbanibulin) is used to treat actinic keratosis of the face or scalp. It is a topical ointment.

Fact Table




US DailyMed


Good oral bioavailability.

Legal status


Chemical Name


Elimination half-life

4 hours

Dosage (Strength)

1% Ointment 5 single use packs of 0.25g


Consult Doctor



Protein binding


PubChem CID






ATC code






Routes of administration



Klisyri ointment comes in packets that contain 1% tirbanibulin. Each packet contains one single dose. 

The instructions that come with your Klisyri prescription should be followed.

Apply Klisyri ointment evenly to the affected area(s) on the face or scalp once daily for 5 days using one single-dose packet. The packet should be disposed of in the trash after use. 

After applying the ointment, you should wash your hands thoroughly with soap and water. After applying the ointment, avoid touching the treated area for 8 hours. Avoid contact with your eyes or mouth.


Tirbanibulin is the active ingredient contained in Klisyri.


  • Before beginning treatment with Klisyri, let your doctor know:
    • If you take any medications, including over-the-counter and prescription medications
    • If you have any allergies
    • Of any health conditions you may have
    • If you are currently pregnant or plan to become pregnant
    • If you are breastfeeding or plan to breastfeed
  • You should not get Klisyri ointment in your eyes as eye irritation may occur. If you accidentally get the ointment in your eyes, flush your eyes with water and seek medical attention.
  • Skin reactions at the site of application may occur with use of Klisyri.

Side Effects

  • Local skin reactions and itching and pain at the application site may be caused by Klisyri. Immediately inform your doctor if you develop concerning or persistent side effects.


Klisyri (tirbanibulin) ointment, for topical use. Exton, PA: Almirall, LLC; 2020.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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