Keytruda (Pembrolizumab)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Keytruda (pembrolizumab) is a medication given through a vein to treat:

  • Advanced non-small cell lung cancer
  • High-risk non-muscle invasive bladder cancer
  • Advanced MSI-H/dMMR colorectal cancer
  • Advanced triple-negative breast cancer
  • Advanced cervical cancer
  • Advanced liver cancer
  • Cutaneous squamous cell carcinoma
  • Melanoma
  • Advanced urothelial bladder cancer
  • Microsatellite instability-high colorectal cancer
  • Classical Hodgkin lymphoma
  • Advanced MSI-H/dMMR endometrial cancer
  • Advanced Merkel cell carcinoma
  • Head and neck squamous cell carcinoma
  • Kidney cancer
  • High-risk early-stage triple-negative breast cancer
  • Advanced gastric cancer
  • Primary mediastinal B-cell lymphoma
  • Advanced esophageal cancer


Your healthcare provider will tell you how much Keytruda you should receive and how often you should receive it. Your dose will be administered through an IV by your healthcare provider. The administration usually takes 30 minutes.

If you have any questions or concerns, talk to your doctor.


Pembrolizumab, a programmed death receptor-1 (PD-1)-blocking antibody, is the active ingredient in Keytruda. L-histidine, polysorbate 80, sucrose, and Water for Injection are the inactive ingredients.


According to the Prescribing Information, there are no contraindications to Keytruda.


  • Before you start receiving Keytruda, tell your doctor about:
    • All the medications you take, including prescription and nonprescription medications
    • Your allergies
    • Your health history and current medical problems
    • Your status of pregnancy of breastfeeding
  • Severe or life-threatening immune system problems, such as pneumonitis, colitis, hepatitis, endocrinopathies, nephritis with kidney impairment, dermatological reactions, and solid organ transplant rejection, can occur with Keytruda treatment.
  • Infusion-related reactions, including hypersensitivity and anaphylaxis, can occur with Keytruda treatment.
  • Patients who receive allogeneic hematopoietic stem cell transplantation (HSCT) may experience serious or life-threatening complications with Keytruda treatment. These complications include hyperacute graft-versus-host-disease (GVHD), acute GVHD, chronic GVHD, hepatic veno-occlusive disease (VOD). These can occur despite intervening therapy.
  • Keytruda should not be administered with a thalidomide analogue and dexamethasone in patients with multiple myeloma. The only exception is if the patient is participating in clinical trials.
  • Harm to a fetus can occur with Keytruda treatment; therefore, effective birth control methods should be used by women of childbearing age.

Side Effects

Fatigue, musculoskeletal pain, rash, diarrhea, fever, cough, decreased appetite, itching, shortness of breath, constipation, pain, stomach pain, nausea, and hypothyroidism are common Keytruda side effects; however, these may not be all the side effects that can occur. If you have side effects that bother you or won’t go away, let your doctor know immediately.

Learn more about Keytruda (pembrolizumab) and the Keytruda cost here.


  1. Keytruda (pembrolizumab) injection, for intravenous use. Whitehouse Station, NJ: Merck and Co., Inc.; 2023.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

product reviews icon Product Reviews