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Ketorolac (Tromethamine)

Prescription medicineOnly Available By Prescription

Top Generic choice

Strength Pack Size Qty
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Your doctor may prescribe ketorolac for many uses including the treatment of moderate and severe migraine or general pain management. Ketorolac is a non-narcotic pain medication and can be prescribed for short periods.

Fact Table







Legal status


Chemical Name


Elimination half-life

3.5 h to 9.2 h

Dosage (Strength)



not recommended



Protein binding


PubChem CID






ATC code






Routes of administration

By mouth


The standard dosage is 10 mg every 4-6 hours as needed. The maximum daily dose is 40 mg per day.


The active ingredient in Ketorolac is ketorolac tromethamine. This medication is a non-steroidal antiinflammatory drug (NSAID).


There are many potential drug-drug interactions with ketorolac. Tell your doctor and pharmacist if you are taking any of the following:

  • Acemetacin
  • Aminolevulinic Acid
  • Apixaban
  • Aspirin
  • Bemiparin
  • CycloSPORINE
  • Dabigatran Etexilate
  • Edoxaban
  • Enoxaparin
  • Heparin
  • Ketorolac (nasal)
  • Lithium
  • Loop diuretics
  • Macimorelin
  • Methotrexate
  • Mifamurtide
  • Nonsteroidal anti-inflammatory agents
  • Pentoxifylline
  • Phenylbutazone
  • PRALAtrexate
  • Probenecid
  • Rivaroxaban
  • Salicylates
  • Selective serotonin reuptake inhibitors
  • Sincalide
  • Sodium phosphates
  • Tenofovir products
  • Tenoxicam
  • Urokinase
  • Vitamin K antagonists


Tell your doctor if you have a history of stomach problems before taking this medication. It can cause stomach problems like bleeding and ulcers. 

Ketorolac can be toxic to the kidney in high doses or taken for a long period. 

Do not take ketorolac along with other NSAIDs like ibuprofen and naproxen.

Side Effects

Some of the most common ketorolac side effects can include: 

  • Abdominal pain
  • Alopecia
  • Anemia
  • Anorexia
  • Asthma
  • Blurred vision
  • Cardiac failure
  • Constipation
  • Cough
  • Cystitis
  • Diaphoresis
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Dyspepsia
  • Dysuria
  • Ecchymoses
  • Edema
  • Esophagitis
  • Exacerbation of urinary frequency
  • Fever
  • Flatulence
  • Gastritis
  • Gastrointestinal fullness
  • Gastrointestinal hemorrhage
  • Gastrointestinal perforation
  • Gastrointestinal ulcer
  • Headache
  • Heartburn
  • Hematemesis
  • Hematuria
  • Hepatitis
  • Hypertension
  • Increased appetite
  • Increased liver enzymes
  • Increased thirst
  • Infertility
  • Jaundice
  • Melena
  • Nausea
  • Oliguria
  • Pallor
  • Palpitations
  • Prolonged bleeding time
  • Proteinuria
  • Pruritus
  • Purpuric disease
  • Renal function abnormality
  • Skin photosensitivity
  • Skin rash
  • Stomatitis
  • Syncope
  • Tachycardia
  • Tinnitus
  • Urinary retention
  • Urticaria
  • Vomiting
  • Weight changes


Ketorolac (Tromethamine). Nutley, NJ: Roche Laboratories Inc.; 2008.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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