Kesimpta (Ofatumumab)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Kesimpta (ofatumumab) is a prescription medication for treating relapsing forms of multiple sclerosis (MS) in adults. It is a monoclonal antibody that targets CD20-positive B-cells, which are involved in the inflammation and damage seen in MS.

Kesimpta is available in a prefilled syringe form and is administered subcutaneously once monthly.

Fact Table







Legal status


Chemical Name


Elimination half-life

14 days

Dosage (Strength)



Consult Doctor



Protein binding

Limited information

PubChem CID

Not Available




Not Available

ATC code






Routes of administration



The first injection of Kesimpta should be administered under the guidance of a licensed healthcare professional.

The usual regimen is as follows:

  • Day 1: 20 mg injection
  • Day 8: 20 mg injection
  • Day 15: 20 mg injection
  • Day 29: 20 mg injection
  • Every 4 weeks thereafter: 20 mg injection

If a dose of Kesimpta is missed, it should be administered as soon as possible. However, if the missed dose is more than four weeks late, the next dose should be administered on the originally scheduled day.


The active ingredient in Kesimpta is ofatumumab.


There are many potential drug interactions, including:

  • Abrocitinib
  • Baricitinib
  • BCG Products
  • Cladribine
  • Coccidioides immitis Skin Test
  • COVID-19 Vaccines
  • Dengue Tetravalent Vaccine
  • Denosumab
  • Deucravacitinib
  • Filgotinib
  • Influenza Virus Vaccines
  • Leflunomide
  • Mumps- Rubella- or Varicella-Containing Live Vaccines
  • Nadofaragene Firadenovec
  • Natalizumab
  • Ocrelizumab
  • Pimecrolimus
  • Poliovirus Vaccine
  • Polymethylmethacrylate
  • Rabies Vaccine
  • Ruxolitinib
  • Sipuleucel-T
  • Tacrolimus
  • Talimogene Laherparepvec
  • Tertomotide
  • Tofacitinib
  • Typhoid Vaccine
  • Upadacitinib
  • Vaccines (Inactivated/Non-Replicating)
  • Vaccines (Live)
  • Yellow Fever Vaccine


Before starting Kesimpta, patients should be tested for hepatitis B virus infection and should be vaccinated against it if needed. Patients should also be screened for tuberculosis.

During treatment with Kesimpta, patients should be monitored for signs of infection, including fever, chills, cough, and sore throat.

Side Effects

Common adverse reactions include:

  • Anemia
  • Back pain
  • Bronchitis
  • Chills
  • Cough
  • Decreased serum immunoglobulins
  • Diarrhea
  • Dyspnea
  • Fatigue
  • Fever
  • Headache
  • Hepatitis B
  • Herpes zoster infection
  • Hyperhidrosis
  • Hypertension
  • Hypogammaglobulinemia
  • Hypotension
  • Infection
  • Influenza
  • Infusion-related reaction
  • Injection site reaction
  • Insomnia
  • Muscle spasm
  • Nasopharyngitis
  • Neutropenia
  • Peripheral edema
  • Pneumonia
  • Porphyria cutanea tarda
  • Progressive multifocal leukoencephalopathy
  • Sepsis
  • Serious Infection
  • Sinusitis
  • Skin rash
  • Stevens-Johnson syndrome
  • Tachycardia
  • Tumor lysis syndrome
  • Upper respiratory tract infection
  • Urinary tract infection
  • Urticaria


Kesimpta [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2020.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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