Jadenu (Deferasirox)

Prescription medicineOnly Available By Prescription
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Top brand choice

Strength Pack Size Qty
Strength
90mg
Pack Size
Qty
Strength
180mg
Pack Size
Qty
Strength
360mg
Pack Size
Qty

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

Top Generic choice

Strength Pack Size Qty
Strength
90mg
Pack Size
Qty
Strength
180mg
Pack Size
Qty
Strength
360mg
Pack Size
Qty

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Jadenu is a chelating agent, and Jadenu uses include lowering iron in the blood of people who have higher-than-average iron levels after a blood transfusion. After receiving this medication, a person requires ongoing monitoring and therapy. It should only be prescribed by a physician trained in using chelating agents.

Jadenu is an iron-chelating agent that works by attaching to high levels of iron and the blood to decrease serum iron concentrations. After binding to iron, the Jadenu-iron complex is excreted in the feces.

Fact Table

Formula

C21H15N3O4

License

EU EMA, US FDA

Bioavailability

70%

Legal status

Rx Only

Chemical Name

Deferasirox

Elimination half-life

8 to 16 hours

Dosage (Strength)

90mg, 180mg, 360mg

Pregnancy

No known Risks

Brands

Exjade, Jadenu

Protein binding

99%

PubChem CID

214348

MedlinePlus

a606002

ChEBI

49005

ATC code

V03AC03

DrugBank

DB01609

KEGG

D03669

Routes of administration

By mouth

Directions

Jadenu is dosed according to weight. Do not change your dosage without first speaking with the prescriber. The dose is usually adjusted every 3-6 months based on blood iron levels. 

Ingredients

The active ingredient in Jadenu is deferasirox.

Interactions

Common drug-drug interactions with Jadenu and other medications can include:

  • Aluminum Hydroxide
  • Amodiaquine
  • Alosetron
  • Bendamustine
  • Bile Acid Sequestrants
  • Busulfan
  • Fosphenytoin
  • Phenytoin
  • Phenobarbital
  • Rasagiline
  • Ritonavir
  • Rifampin
  • Selexipag
  • Theophylline
  • Tizanidine

If you take any of the above medications, you should discuss them with your doctor or pharmacist.

Cautions

Gastrointestinal bleeds can occur while taking this drug, and they are more common in older adults.

Jadenu can cause kidney or liver failure in certain patients. Your prescribing doctor should monitor for these conditions once you buy Jadenu and begin treatment.

Use caution if you have a history of eye or ear problems before taking this medication.

Tell your doctor if you experience a skin rash while using Jadenu.

Side Effects

Common Jadenu side effects may include:

  • Abdominal pain
  • Acute pancreatitis
  • Anxiety
  • Cholelithiasis
  • Diarrhea
  • Dizziness
  • Duodenal ulcer
  • Dyschromia
  • Edema
  • Fanconi's Syndrome
  • Fatigue
  • Gastrointestinal hemorrhage
  • Gastritis
  • Increased liver enzymes
  • Nausea
  • Proteinuria
  • Serum creatinine increase
  • Skin rash
  • Sleep disorder
  • Vomiting

References

Jadenu [package insert]. East Hanover, NJ: Novartis; 2020.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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