Itulatek (Betula Verrucosa) Sublingual

Description

Itulatek is available by prescription only for the treatment of moderate to severe seasonal allergies due to pollen from birch, alder, and/or hazel in adults who did not experience relief with other treatments and had a positive pollen of birch, alder, or hazel sensitization test.

Itulatek comes in 1 mg tablets for placement underneath the tongue.

Directions

Take Itulatek as directed by your doctor. Your first dose should be administered by a healthcare professional with at least a 30-minute observation.

Recommended dose: Place one tablet (1 mg) under the tongue to dissolve once daily. Avoid taking it with food or drinks. Do not swallow for about one minute after taking. Do not consume food or drink within five minutes of taking it. Wash your hands after touching the tablet.

If you have any questions or concerns, ask your doctor or pharmacist.

Ingredients

Which birch (Betula verrucosa), a standardized allergen extract, makes up Itulatek. The inactive ingredients include fish gelatin, mannitol, and sodium hydroxide (for balancing pH).

Contraindications

Do not take Itulatek if you have an allergy to any Itulatek’s ingredients.

Do not take Itulatek if you have had a prior severe systemic allergic reaction to birch or related tree pollen immunotherapy.

Do not take Itulatek if you have asthma that is unstable, severe, or uncontrolled.

Do not take Itulatek if you are taking beta-blockers such as propranolol.

Do not take Itulatek if you have active oral inflammatory conditions such as oral lichen planus with ulcerations, severe fungal infections, or dental extraction.

Do not take Itulatek if you have had eosinophilic esophagitis.

Cautions

Itulatek has the following Warnings and Precautions:

• Itulatek treatment should only be prescribed and initiated by physicians who are adequately trained and experienced in the treatment of respiratory allergic diseases.

• Systemic allergic reactions, including severe local allergic reactions, can occur and may require emergency administration of epinephrine, bronchodilators, or systemic corticosteroids.

• The first dose of Itulatek must be taken in the doctor’s office under medical supervision with a 30-minute observation.

• Before you begin treatment with Itulatek sublingual immunotherapy for allergies, tell your doctor about:
• All the medications you take, including prescription and over-the-counter medications
• Your allergies
• Your health history and current medical problems
• Your pregnancy or breastfeeding status
• Local swelling may occur with Itulatek treatment. The swelling may become severe. Stop taking Itulatek if this occurs.
• Itulatek should not be administered to pregnant women.
• Use caution if you have active systemic autoimmune disorders, immune problems, or malignant neoplasia.
• Eosinophilic esophagitis can occur with Itulatek treatment.
• Severe reactions that can become life-threatening may occur with Itulatek use. Fainting, low blood pressure, rapid heart rate, runny dose, sneezing, shortness of breath, wheezing, trouble breathing, chest discomfort, stomach pain, vomiting, diarrhea, rash, itching, flushing, and hives are symptoms associated with these reactions. Seek emergency care right away if you develop any of these reactions. You may be at increased risk if you have certain heart problems, including unstable angina (chest pain), recent heart attack, significant heart arrhythmias, and uncontrolled high blood pressure.
• If you have oral inflammation or a wound, it is recommended to temporarily stop taking Itulatek until you are healed.
• Do not take Itulatek if you have severe asthma that is not stable or uncontrolled.

Side Effects

Itching of the ears, mouth, or tongue; swelling of the mouth, tongue, lips, or throat; cough; throat pain or irritation; and numbness or prickling sensation of the mouth are common Itulatek side effects; however, other side effects may occur. If you have side effects that worry you or will not resolve, contact your doctor right away.

You can buy Itulatek sublingual allergy immunotherapy tablets online at a competitive price and with a valid prescription from your doctor here.

Reference:

1. Itulatek. Horsholm, Denmark: ALK-Abello A/S; 2021.
2. Itulatek. ALK-Abello A/S; 2022.

About Dr. Savannah Muncy (Page Author)

Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....