Itovebi (Inavolisib)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
Strength
3mg
Pack Size
Qty
Strength
9mg
Pack Size
Qty
What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Itovebi (Inavolisib) is used in combination with palbociclib and fulvestrant to treat certain breast cancers that have become resistant to hormone therapy. More specifically, it treats hormone receptor–positive (HR+), HER2-negative advanced, or metastatic breast cancer with a PIK3CA gene mutation in adult patients. In blocking the PI3K-alpha enzyme, which cancer cells with the PIK3CA mutation rely on to grow and survive, Itovebi helps slow tumor growth and disease progression.

Directions

You can buy the Itovebi drug, which is available as an oral tablet, in 3 mg and 9 mg strengths. Itovebi should be taken exactly as prescribed, in combination with palbociclib and fulvestrant, never as a monotherapy. Your doctor may also prescribe additional medications as part of your treatment plan to lower your hormone levels and improve the effectiveness of Itovebi.

While 9 mg once daily is the typical dose of Itovebi, your doctor may prescribe 6 mg or 3 mg once daily instead. For example, a lower dose may be needed if your kidney function is impaired or side effects are severe. Always swallow Itovebi whole with or without food. Do not chew, crush, or split the tablet.

Itovebi should be taken at approximately the same time each day. If you miss a dose, take it as soon as possible within nine hours. If nine hours have passed, skip it and take the next scheduled dose. If you vomit, do not take an additional dose and resume with your regular dosing schedule the next day.

Itovebi is taken until it stops being effective or side effects become intolerable.

Ingredients

The active ingredient in Itovebi is inavolisib.

Inactive ingredients are lactose, magnesium stearate, microcrystalline cellulose, sodium starch glycolate, iron oxide red, iron oxide yellow (9 mg tablet only), macrogol/polyethylene glycol, polyvinyl alcohol (partially hydrolyzed), talc, and titanium dioxide.

Contraindications

According to the FDA, Itovebi has no contraindications. However, your doctor will determine whether you can take Itovebi on an individual basis.

Cautions

  • Before taking Itovebi, inform your doctor of
    • Other medical conditions, especially diabetes, kidney or liver issues, heart conditions, digestive and mouth disorders, prior cancer treatments, allergies, pregnancy, breastfeeding status, and fertility concerns.
    • All the medications you’re taking, including over-the-counter drugs and herbal or vitamin supplements.
    • Your pregnancy and breastfeeding status. Avoid pregnancy during treatment as Itovebi can harm an unborn baby. Do not breastfeed while taking Itovebi or for at least 1 week after your last dose.
  • Do not take Itovebi if you’re allergic to one of its ingredients. Seek immediate medical care if you experience allergy symptoms such as rash, itching, swelling, or trouble breathing.
  • Inform your doctor if you notice unusual thirst, frequent urination, or blurred vision (symptoms of high blood sugar), as Itovebi may increase blood sugar levels.
  • Contact your doctor if your mouth becomes painful or swollen, since Itovebi can cause soreness or ulcers. You may be prescribed a mild steroid mouthwash to prevent or reduce this side effect.
  • Consult your doctor if you experience persistent diarrhea and stay hydrated, since this side effect may lead to dehydration or kidney problems when severe.
  • Your doctor will monitor your blood sugar, liver function, and electrolyte levels using blood tests, and may adjust your Itovebi dose or that of other medications if needed.
  • You may need a lower dose of Itovebi if you have severely reduced kidney or liver function.

Side Effects

High blood sugar, fatigue, mouth sores, diarrhea, nausea, vomiting, appetite loss, skin rash, and dryness are common but manageable side effects. Severe side effects requiring medical attention include severe hyperglycemia or infections, increased liver enzymes, allergic reactions, or fetal harm.

These are not all possible Itovebi side effects. Seek medical care immediately if you experience persistent or severe side effects of Itovebi.

Buy Itovebi safely and hassle-free at Canada Drugs Direct! All you need is a valid prescription from your healthcare provider.

IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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