Also Known as Isoptin KKH,Cordilox SR, Calaptin SR
Only Available By Prescription
Top brand choice
| Strength | Pack Size | Qty | |
|---|---|---|---|
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Strength
120mg
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Top Generic choice
| Strength | Pack Size | Qty | |
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Strength
120mg
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Strength
240mg
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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Isoptin SR contains a calcium channel blocker that slows down the flow of calcium into the muscle cells of the heart and blood vessels. It can help relax blood vessels and make it easier for the heart to pump blood. Isoptin SR is approved to treat high blood pressure (hypertension) in adults.
| Fact Table | |
| Formula | C27H38N2O4 |
| License | US FDA |
| Bioavailability | 20–35% |
| Legal status | Prescription only (Rx-only) |
| Chemical Name | (RS)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-isopropylvaleronitrile |
| Elimination half-life | 4.5–12 hours (extended with SR) |
| Dosage (Strength) | 120 mg, 180 mg, 240 mg sustained-release tablets |
| Pregnancy | Category C (use only if clearly needed) |
| Brands | Isoptin SR, Calan SR, Verelan, Covera-HS |
| Protein binding | 90% |
| PubChem CID | 2520 |
| MedlinePlus | a684027 |
| ChEBI | 10118 |
| ATC code | C08DA01 |
| DrugBank | DB00661 |
| KEGG | D08657 |
| Routes of administration | Oral (sustained-release tablet), IV (hospital use) |
Take Isoptin SR by mouth, usually with food. The typical starting dosage is 180 mg in the morning; a healthcare provider may adjust the dose up to 240 mg taken in the morning or in the morning and evening. The maximum dosage is 480 mg per day. Swallow the tablets whole. Do not crush or chew them. Use the medication at the same time each day to help maintain its effectiveness.
Isoptin SR contains the active ingredient Verapamil.
Avoid taking or using this medication if any of the following apply:
Common side effects of Isoptin SR include constipation, dizziness, nausea, and headache. Fatigue, swelling (edema), and slow heart rate (bradycardia) have also been reported in a small number of patients. In clinical trials, constipation was the most frequent side effect, affecting up to around 7% of users. While most side effects are mild, patients should let their doctor know if symptoms persist or worsen.
More serious effects such as severely low blood pressure, heart block, or worsening heart failure may occur, especially in people with existing heart problems. Rare reactions include liver enzyme changes, allergic reactions, skin rash, and vision problems. Post-marketing reports have also mentioned erectile dysfunction, muscle pain, and hypersensitivity reactions. If you experience breathing trouble, significant swelling, or an irregular heartbeat, seek medical attention.
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If you have any questions at all, or would like to place an order, you are encouraged to contact us by toll-free
phone 1-888-904-8467 or email info@canadadrugsdirect.com.
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Canada Drugs Direct employs dedicated, professional licensed pharmacists to ensure that each and every order is reviewed before it is dispensed for the safety and health of our customers. At CanadaDrugsDirect.com, your health is our top priority.
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