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Isentress (Raltegravir)

Prescription medicineOnly Available By Prescription

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You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


ISENTRESS (Raltegravir) is an oral medication prescribed to treat Human Immunodeficiency Virus (HIV) infection. In people with HIV infection, the virus attacks the cells of their immune system. If left untreated, they develop Acquired Immunodeficiency Syndrome (AIDS). 

When the HIV virus enters the body, it hijacks cells of the immune system. It then uses these cells to replicate. ISENTRESS works by preventing HIV viruses from reproducing. If treated early, ISENTRESS and other medications can help push HIV infection in remission.


To be effective, ISENTRESS must be taken exactly as prescribed every day.

For people just starting the medication, they can take it either:

  • 400 mg by mouth twice daily
  • 1200 mg by mouth once daily

Patients who have been using ISENTRESS for awhile should take 400 mg twice daily.


The active ingredient in ISENTRESS is raltegravir.


Drug interactions with ISENTRESS can be severe. Some interactions create a harmful combination where too much drug is in the body. Some interactions reduce the amount in the body and make the drug ineffective.

The following drugs interact with ISENTRESS:

  • Aluminum or magnesium-containing antacids
  • Calcium carbonate
  • Carbamazepine
  • Etravirine
  • Fosamprenavir
  • Phenobarbital
  • Phenytoin
  • Rifampin
  • Tipranavir/ritonavir


ISENTRESS is known to cause rare and serious skin reactions. Tell your doctor right away if you get a rash or skin problems after starting ISENTRESS.

Pregnant patients should only use the twice-daily dosing of ISENTRESS.

Your doctor should monitor for Immune Reconstitution Syndrome while taking ISENTRESS.

Patients with phenylketonuria should use caution while taking chewable ISENTRESS because it contains phenylalanine.

Side Effects

Common ISENTRESS side effects include:

  • Dizziness
  • Fatigue
  • Headache
  • Insomnia
  • Nausea


Isentress [package insert]. Whitehouse Station, NJ: Merck; 2007.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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