Iopidine Eye Drops (Apraclonide)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
0.5% 5ml
Pack Size

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Iopidine Eye Drops (Apraclonidine) are a prescription medication used to lower increased pressure in the eyes, particularly in cases of open-angle glaucoma or ocular hypertension. Iopidine works by decreasing the amount of fluid within the eye, reducing pressure and helping prevent damage to the optic nerve.

Fact Table




US DailyMed


Rapid absorption through the cornea

Legal status


Chemical Name


Elimination half-life

3 hours

Dosage (Strength)

0.5% 5ml


Consult Doctor


Iopidine Eye Drops

Protein binding


PubChem CID






ATC code






Routes of administration

Ophthalmic (eye drops)


The Iopidine Eye Drops dosage is typically one drop in the affected eye(s) three times daily. Wash your hands thoroughly before using the eye drops, and avoid touching the dropper tip with your fingers to prevent contamination. Remove contact lenses before administering and wait until 15 minutes after before reinserting the contact lenses. Follow the dosage instructions as prescribed by your healthcare provider.


The active ingredient in Iopidine Eye Drops is apraclonidine.


Avoid using Iopidine Eye Drops if you have a history of any of the following:

  • Allergy or hypersensitivity to apraclonidine or any ingredients in Iopidine Eye Drops
  • Current use of monoamine oxidase inhibitors (MAOIs)


  • Before you start using Iopidine Eye Drops, discuss with your doctor:
    • Any allergies you may have
    • Any medications you take, including over-the-counter medicines, vitamins, and supplements
    • Any eye problems or diseases, like macular edema or uveitis
    • If you are pregnant, planning to become pregnant, or breastfeeding
    • If you plan to have eye surgery
  • Iopidine Eye Drops may cause drowsiness, temporary blurring of vision, or other visual changes; do not drive or operate heavy machinery until you know how the medication affects you.
  • Iopidine Eye Drops can be absorbed into your system and may affect other parts of your body, including your heart or blood vessels, so use them only as directed.
  • Store Iopidine Eye Drops at room temperature away from light and moisture.
  • Seek medical help if you experience signs or symptoms of an allergic reaction, such as severe swelling, hives, or trouble breathing.
  • Rare cases of depression have been reported with Iopidine Eye Drops. Consult a healthcare provider with any previous mental health diagnoses before starting treatment.
  • Do not touch the dropper tip to any surface to prevent contamination.

Side Effects

Common side effects of Iopidine Eye Drops may include itchiness, dryness, or discomfort in the eyes, dry mouth, and a sensation of an object stuck in the eye. Other potential side effects may include dry nose, headache, nervousness, nausea, and changes in taste. Severe side effects, such as chest pain or severe allergic reactions, may require immediate medical attention.

Consult a healthcare provider for other possible side effects, warnings, and precautions.


Iopidine Eye Drops Prescribing Information. Fort Worth, TX: Alcon Laboratories; 2016.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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