Intal Inhaler (Cromolyn)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Intal Inhaler contains cromolyn sodium, a mast cell stabilizer indicated for the prophylactic management of bronchial asthma in both pediatric and adult patients. It works by inhibiting the degranulation of sensitized mast cells and preventing the release of inflammatory mediators such as histamine and leukotrienes, which are responsible for bronchospasm and airway inflammation. Intal is not a bronchodilator and is not effective for the relief of acute asthma attacks. Regular use is essential to achieve and maintain therapeutic benefit in controlling chronic asthma symptoms.

Fact Table

Formula

C23H14Na2O11

License

US FDA (Intal withdrawn from U.S. market)

Bioavailability

~8% (inhaled); majority excreted unchanged

Legal status

Prescription (formerly)

Chemical Name

Disodium cromoglycate

Elimination half-life

~1.3 hours

Dosage (Strength)

800 mcg per actuation (typical adult dose: 2 puffs QID)

Pregnancy

Category B – no proven risk in humans

Brands

Intal, generic cromolyn (oral and ophthalmic forms available)

Protein binding

~65%

PubChem CID

5281075

MedlinePlus

a600014

ChEBI

3746

ATC code

R03BC01

DrugBank

DB01003

KEGG

D00397

Routes of administration

Inhaled (MDI), oral, ophthalmic, nasal

Directions

The usual recommended dosage for adults and children over 5 years of age is:

Two inhalations (1 mg per actuation, total 2 mg) four times daily, administered via oral inhalation.

To use, shake the inhaler well and exhale fully before each inhalation. Inhale deeply while pressing down on the canister and hold breath for several seconds before exhaling. Rinse mouth after use to minimize irritation. Patients should be instructed on proper inhaler technique. Dose reduction may be considered after clinical improvement is maintained. Intal must be used regularly, and maximum benefit may take 2 to 4 weeks to be observed.

Ingredients

Each actuation of Intal delivers:

Cromolyn sodium 1 mg

Inactive ingredients may include:

Propellants such as CFC-12 and CFC-114, depending on the formulation and market availability

(Note: Many CFC formulations have been phased out in favor of environmentally safer propellants.)

Contraindications

Intal is contraindicated in patients with:

Known hypersensitivity to cromolyn sodium or any component of the formulation

Acute asthma attacks requiring immediate bronchodilation

Cautions

Intal is a preventative treatment and should not be used for rapid symptom relief. Patients should continue their prescribed bronchodilator for acute attacks. Sudden withdrawal from systemic corticosteroids may result in adrenal insufficiency; tapering must be gradual and under medical supervision. Intal may not be effective in all patients, and response should be evaluated within several weeks. Use in pregnancy appears to be safe, but consult a healthcare provider before use. Not intended for use in children under 5 years of age unless prescribed.

Side Effects

Common and potential side effects include:

Throat irritation

Cough or hoarseness

Unpleasant taste

Sneezing or nasal congestion (if inhaled improperly)

Rare: bronchospasm, skin rash, or hypersensitivity reactions

IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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