Inspra (Eplerenone)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


INSPRA (eplerenone) can be prescribed to treat two different heart conditions. INSPRA lowers blood pressure, so it can treat hypertension. It also reduces the amount of pressure in the heart and is useful for treating congestive heart failure (CHF).

Hypertension is a chronic condition where the blood pressure is too high. The symptoms often go unnoticed, but high pressure causes damage to different organs over time.

Heart failure is also a chronic condition where the heart muscle cannot pump blood as effectively as it should. People with heart failure have fluid that backs up into their body (edema) or into their lungs.


The INSPRA (eplerenone) dose may be different depending on the condition being treated. Take it exactly as prescribed by the doctor.

For hypertension, the starting dose is 50 mg by mouth once daily. The dose may be increased to a maximum of 50 mg twice daily.

For heart failure, the starting dose is 25 mg by mouth once daily. The dose may be increased to a maximum of 50 mg once daily after at least four weeks.


The active ingredient in INPRA is eplerenone.


Tell your doctor or pharmacist your entire medication list so they can screen for drug interactions. The most common interactions may include:

  • ACE inhibitors
  • Angiotensin Receptor Blockers
  • Erythromycin
  • Fluconazole
  • Lithium
  • NSAIDs
  • Saquinavir
  • Verapamil


Tell your doctor if you have a history of diabetes with microalbuminuria or a history of kidney problems.

INSPRA may cause high blood potassium, especially when used with other diuretics or blood pressure medications. Your doctor will check your potassium when starting the medication. They should also check it periodically while taking INSPRA.

Side Effects

INSPRA side effects may include the following:

  • Coughing
  • Diarrhea
  • Dizziness
  • Fatigue
  • Flu-like symptoms
  • Hyperkalemia (high blood potassium)
  • Increased creatinine

Tell your doctor if you experience any of the above while taking INSPRA.


Inspra [package insert].New York, NY: Pfizer; 2002.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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