Top brand choice
Strength | Pack Size | Qty | |
---|---|---|---|
Strength
5/12.5mg
|
We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Inhibace Plus is a combination medication for managing high blood pressure (hypertension). It combines cilazapril, an ACE inhibitor, with hydrochlorothiazide (HCTZ), a diuretic. By lowering blood pressure, Inhibace Plus helps reduce the risk of strokes, heart attacks, and kidney problems.
Cilazapril relaxes blood vessels, making it easier for the heart to pump blood. Hydrochlorothiazide helps the body eliminate excess salt and water through urine, further aiding in lowering blood pressure.
Fact Table |
|
Formula |
C22H31N3O5 (Cilazapril) + C7H8ClN3O4S2 (HCTZ) |
License |
EMA |
Bioavailability |
60-70% (Cilazapril) + 70% (HCTZ) |
Legal status |
Prescription only |
Chemical Name |
(RS)-1-[2-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid (Cilazapril) + 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide (HCTZ) |
Elimination half-life |
9 hours (Cilazaprilat, active metabolite) + 5.6-14.8 hours (HCTZ) |
Dosage (Strength) |
Cilazapril 5 mg + HCTZ 12.5 mg tablets |
Pregnancy |
Contraindicated |
Brands |
Inhibace Plus |
Protein binding |
30% (Cilazapril) + 40-70% (HCTZ) |
PubChem CID |
5282383 (Cilazapril) + 3639 (HCTZ) |
MedlinePlus |
a601040 (HCTZ) |
ChEBI |
CHEBI:35880 (Cilazapril) + CHEBI:3707 (HCTZ) |
ATC code |
C09BA08 |
DrugBank |
DB01340 (Cilazapril) + DB00999 (HCTZ) |
KEGG |
D01866 (Cilazapril) + D00360 (HCTZ) |
Routes of administration |
Oral |
Take Inhibace Plus exactly as your doctor prescribed.
The active ingredients in Inhibace Plus are cilazapril and hydrochlorothiazide.
Common drug-drug interactions may include:
Before using Inhibace Plus, inform your doctor if you have a history of kidney or liver problems, electrolyte imbalances, or gout.
Pregnant or breastfeeding women should avoid using this medication, as it may harm the baby. Consult your doctor immediately if you become pregnant while taking Inhibace Plus.
Do not use Inhibace Plus if you are allergic to cilazapril, hydrochlorothiazide, or any other medication ingredients.
Common side effects may include:
Apo-cilazapril/HCTZ [product monograph]. Toronto, ON: Apotex; November 2017.