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Imuran (Azathioprine)

Prescription medicineOnly Available By Prescription
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Top brand choice

Strength Pack Size Qty
Strength
25mg
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Strength
50mg
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Top Generic choice

Strength Pack Size Qty
Strength
50mg
Pack Size
Qty

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Imuran is a medication prescribed to treat a variety of diseases that are regulated by the immune system. Some examples include organ transplant rejection prophylaxis, Crohn's disease, hepatitis, lupus nephritis, rheumatoid arthritis, and ulcerative colitis.

Imuran is converted to active metabolites that incorporate into human cells and prevent DNA replication. While Imuran targets diseased cells, it can also target healthy cells, leading to a long list of side effects.

Fact Table

Formula

C9H7N7O2S

License

US FDA

Bioavailability

60±31%

Legal status

RX Only

Chemical Name

Azathioprine

Elimination half-life

26–80 minutes

Dosage (Strength)

50mg

Pregnancy

Consult Doctor

Brands

Azasan, Imuran

Protein binding

20–30%

PubChem CID

2265

MedlinePlus

a682167

ChEBI

2948

ATC code

L04AX01

DrugBank

DB00993

KEGG

D00238

Routes of administration

By mouth

Directions

The dose varies from disease to disease and person to person. It should be taken exactly as prescribed by the doctor. 

Ingredients

The active ingredient in Imuran is azathioprine.

Interactions

There are many potentially dangerous drug-drug interactions, including:

  • Abrocitinib
  • Allopurinol
  • Baricitinib
  • BCG & BCG Products
  • Cladribine
  • Coccidioides immitis Skin Test
  • COVID-19 Vaccines
  • Deferiprone
  • Dengue Tetravalent Vaccine
  • Denosumab
  • Deucravacitinib
  • Dipyrone
  • Febuxostat
  • Fexinidazole
  • Filgotinib
  • Influenza Virus Vaccines
  • Leflunomide
  • Mercaptopurine
  • Natalizumab
  • Pimecrolimus
  • Poliovirus Vaccine
  • Polymethylmethacrylate
  • Rabies Vaccine
  • Ribavirin
  • Ropeginterferon Alfa-2b
  • Rubella- or Varicella-Containing Live Vaccines
  • Ruxolitinib
  • Sipuleucel-T
  • Tacrolimus
  • Talimogene Laherparepvec
  • Tertomotide
  • Tofacitinib
  • Typhoid Vaccine
  • Upadacitinib
  • Yellow Fever Vaccine

Cautions

Tell your doctor if you have ahistory of liver problems. 

Tell your doctor if you have a history of kidney problems.

The effects of vaccines may be diminished while taking Imuran.

Do not abruptly stop taking this drug, as it could worsen the underlying disease.

Side Effects

Side effects may include:

  • Acute myelocytic leukemia 
  • Alopecia
  • Anemia
  • Aplastic anemia
  • Arthralgia
  • Bone marrow depression
  • Cholestasis 
  • Diarrhea
  • Drug-induced hypersensitivity reaction
  • Erythema nodosum
  • Fever
  • Gastrointestinal hypersensitivity 
  • Hemophagocytic lymphohistiocytosis 
  • Hemorrhage 
  • Hepatic sinusoidal obstruction syndrome
  • Hepatosplenic T-cell lymphomas
  • Hepatotoxicity
  • Hypersensitivity pneumonitis
  • Infection
  • Interstitial pneumonitis
  • JC virus infection
  • Leukopenia
  • Macrocytic anemia
  • Malignant lymphoma
  • Malignant neoplasm of skin
  • Malignant solid tumor
  • Nausea and vomiting 
  • Negative nitrogen balance
  • Neoplasm 
  • NK cell deficiency
  • Pancreatitis 
  • Pancytopenia
  • Progressive multifocal leukoencephalopathy
  • Skin rash
  • Steatorrhea
  • Sweet's syndrome 
  • Thrombocytopenia 

References

Imuran [package insert]. San Diego, CA: Prometheus Laboratories Inc.; 2011.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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