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Imitrex Autoinjector Refill Cartridges

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
6mg/0.5ml cartridge syringes plus 1 autoinjector
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


The Imitrex autoinjector is a prescription medication, designed for the administration of sumatriptan under the skin. Imitrex is a serotonin receptor agonist. Sumatriptan works by decreasing pain and aura in acute migraine episodes and cluster headaches. 

Imitrex works directly on serotonin receptors constricts of cerebral blood vessels, Imitrex ameliorates pain, light and sound sensitivity, alongside concomitant symptoms often associated with migraines. For many patients it enhances the well-being of individuals with neurological disorders.


Take 1-6 mg at the onset of migraine or cluster headache. Do not take more than 12 mg in one day.


The active ingredient in Imitrex Autoinjector is sumatriptan.


Common drug-drug interactions with this medication include:

  • Almotriptan 
  • Bromocriptine
  • Buspirone
  • Droxidopa
  • Eletriptan
  • Ergotamine Dihydroergotamine
  • Frovatriptan 
  • Isocarboxazid (Marplan)
  • Lithium
  • Lorcaserin
  • Moclobemide (Aurorix, Manerix)
  • Monoamine Oxidase Inhibitors
  • Naratriptan 
  • Phenelzine (Nardil)
  • Rizatriptan 
  • Selective serotonin reuptake inhibitors (SSRIs)
  • Selegiline (Emsam)
  • Serotonin-norepinephrine reuptake inhibitors (SNRIs)
  • St. John's Wort (Hypericum Perforatum)
  • Sumatriptan 
  • Tramadol
  • Tranylcypromine (Parnate)
  • Tryptophan
  • Zolmitriptan


Tell your healthcare provider if you have a history of cardiovascular problems, gastrointestinal problems, a history of stroke, or a history of seizures.

Using more than prescribed may cause rebound headaches.

Side Effects

The most common side effects of Imitrex include:

  • Asthenia
  • Bleeding at the injection site
  • Bronchospasm
  • Bruising at the injection site
  • Burning sensation
  • Burning sensation at the injection site
  • Chest discomfort
  • Chest pressure
  • Chest tightness
  • Diaphoresis
  • Dizziness
  • Drowsiness
  • Erythema at the injection site
  • Feeling hot
  • Feeling of heaviness
  • Flushing
  • Headache
  • Local discomfort (jaw or throat)
  • Myalgia
  • Nasal discomfort (nasal cavity)
  • Nausea and vomiting
  • Neck pain
  • Neck stiffness
  • Numbness
  • Pain at the injection site
  • Paresthesia
  • Sedated state
  • Sensation of pressure
  • Sensation of tightness
  • Sinus discomfort
  • Strange feeling
  • Swelling at the injection site
  • Tight feeling in the head
  • Tingling sensation
  • Vertigo
  • Warm sensation at the injection site


  1. Imitrex Injection [package insert]. Research Park Triangle, NJ: GSK; 2015.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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