Humalog (Insulin Lispro)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

HUMALOG (insulin lispro) is a prescription insulin product that is prescribed to treat types 1 and 2 diabetes

Insulin is a naturally-occurring hormone that regulates the amount of glucose that is available in the blood. People with diabetes either do not have enough insulin or have lost sensitivity to insulin. Without enough insulin, their blood glucose is often too high.

HUMALOG insulin replaces normal human insulin and helps to restore healthy levels of blood glucose. When glucose is too high or too low in diabetic patients, it can cause long-term damage.

Fact Table

Formula

C257H383N65O77S6

License

US FDA

Bioavailability

~55–70%

Legal status

Prescription only (Rx-only)

Chemical Name

Insulin Lispro

Elimination half-life

~1 hour

Dosage (Strength)

100 units/mL (U-100), 200 units/mL (U-200); available in 3 mL cartridges, pens, and 10 mL vials

Pregnancy

Consult a doctor (Category B)

Brands

Humalog, Admelog, Lyumjev

Protein binding

Low

PubChem CID

16132453

MedlinePlus

a696015

ChEBI

86337

ATC code

A10AB04

DrugBank

DB00046

KEGG

D04556

Routes of administration

Subcutaneous injection, intravenous (under medical supervision)

Directions

HUMALOG insulin is injected under the skin between 1 to 4 times daily. The dose is individualized and determined by your doctor.

Do not mix HUMALOG with other insulins unless directed to by your doctor.

Ingredients

The active ingredient in HUMALOG is insulin lispro.

Insulin has very few drug interactions. However, use caution with certain drug combinations because they can mask the symptoms of hypoglycemia. Tell your doctor if you are taking the following:

  • Beta-blockers
  • Clonidine
  • Guanethidine
  • Reserpine

Cautions

Review the signs and symptoms of low blood sugar before starting or changing any insulin regimen. Common signs include:

  • Anxiety
  • Fatigue
  • Heart arrhythmia
  • Hunger
  • Irritability
  • Pale skin
  • Sweating
  • Tingling or numbness of the face
  • Tremor

Tell your doctor if you have a heart condition or a history of low potassium.

Tell your doctor if you have a history of kidney and liver dysfunction, as the dose of insulin may need to be adjusted.

Side Effects

The most common side effects of HUMALOG insulin may include:

  • Allergic reactions
  • Hypoglycemia
  • Injection site reactions
  • Lipodystrophy
  • Pruritus
  • Rash

References

  1. Humalog [package insert].Indianapolis, IN: Lilly; 2013.
  2. Insulin Lispro. Drugs.com. April 6th 2020. Retrieved: July 23rd, 2020.

Frequently Asked Questions about Humalog (Insulin Lispro)


How quickly does Humalog start working?

Humalog begins lowering blood sugar about 15 minutes after injection, peaks in 30–90 minutes, and lasts about 2 to 4 hours.


Can I skip meals after taking Humalog?

No. Skipping meals after a Humalog dose increases the risk of hypoglycemia (low blood sugar). You should always eat shortly before or right after your injection.


Is Humalog safe during pregnancy?

Yes. Humalog is often used to manage diabetes during pregnancy, but insulin needs change throughout pregnancy, so close monitoring by a healthcare provider is required.


Can Humalog cause allergic reactions?

Yes, though rare. Allergic reactions can include rash, itching, swelling, or breathing difficulty. Seek immediate medical help if severe symptoms occur.


How do I rotate Humalog injection sites properly?

Inject into the abdomen, thigh, or upper arm, rotating sites within the same region to prevent lipodystrophy (fatty tissue changes). Avoid injecting into the exact same spot repeatedly.


What should I do if I overdose on Humalog?

An overdose can cause severe hypoglycemia, which may lead to unconsciousness or seizures. Treat with fast-acting glucose if symptoms are mild. For severe symptoms, use a glucagon injection and seek emergency care.


Can Humalog be used in type 2 diabetes?

Yes. While more commonly used in type 1 diabetes, Humalog is also prescribed for type 2 diabetes when oral medications aren’t enough to control blood sugar, often with long-acting insulin.


What are signs of low blood sugar while using Humalog?

Common symptoms include:

Sweating
Shakiness
Dizziness
Hunger
Irritability

Severe cases can cause confusion, seizures, or unconsciousness.


Can I reuse Humalog pen needles or syringes?

No. Reusing needles increases the risk of infection, tissue damage, and inaccurate dosing. Always use a new needle for every injection.


Does Humalog require blood sugar testing?

Yes. Frequent blood glucose monitoring is essential to avoid hypoglycemia and to determine if dose adjustments are needed.

IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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